SCHEMBL10596241

SCHEMBL10596241

[CH2]C(=O)c1cc(F)cc(C#N)c1

nearest known ligand 0.54

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
CES2 O00748 1/20 0.45
CES1 P23141 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2825638 0.85 PARP1 (0.46) CES2CES1
SCHEMBL505097 0.82 HCAR1 (0.53) CES2CES1
SCHEMBL1764880 0.81 VNN1 (0.46)
SCHEMBL5222697 0.81 CES2 (0.45) CES2CES1
Hydrochloric Acid SCHEMBL6524503 0.81 HCAR1 (0.52) CES2CES1
SCHEMBL2093012 0.79 CES2 (0.62) CES2CES1
SCHEMBL24022850 0.77
SCHEMBL20646737 0.77
SCHEMBL22557052 0.77 VNN1 (0.43)
SCHEMBL23384719 0.77

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0195396-B1 5-FLUOROBENZONITRILE DERIVATIVES AND PHARMACOLOGICALLY ACCEPTABLE ACID ADDITION SALTS THEREOF FOR INCREASING THE LEAN MEAT TO FAT RATIO, AND/OR ENHANCING THE GROWTH RATE OF WARM-BLOODED ANIMALS AMERICAN CYANAMID COMPANY (US) 1989-03-01 EP claimed