Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ENPP2 | Q13822 | 1/20 | 0.43 |
| ▸ | INPPL1 | O15357 | 1/20 | 0.41 |
| ▸ | AKT1 | P31749 | 1/20 | 0.41 |
| ▸ | INPP5A | Q14642 | 1/20 | 0.41 |
| ▸ | S1PR1 | P21453 | 9/20 | 0.40 |
| ▸ | S1PR3 | Q99500 | 9/20 | 0.40 |
| ▸ | S1PR2 | O95136 | 8/20 | 0.40 |
| ▸ | S1PR4 | O95977 | 7/20 | 0.40 |
| ▸ | PLK1 | P53350 | 1/20 | 0.39 |
| ▸ | LPAR3 | Q9UBY5 | 3/20 | 0.39 |
| ▸ | LPAR2 | Q9HBW0 | 3/20 | 0.39 |
| ▸ | LPAR1 | Q92633 | 2/20 | 0.39 |
| ▸ | S1PR5 | Q9H228 | 3/20 | 0.38 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.37 |
| ▸ | CETP | P11597 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL456734 | 1.00 | ENPP2 (0.43) | ENPP2INPPL1AKT1INPP5AS1PR1 | |
| SCHEMBL456732 | 0.88 | ENPP2 (0.38) | ENPP2ALOX5 | |
| SCHEMBL9329182 | 0.87 | TYR (0.42) | ENPP2INPPL1AKT1INPP5AS1PR1 | |
| SCHEMBL29065640 | 0.87 | ALOX5 (0.42) | ENPP2INPPL1AKT1INPP5AS1PR1 | |
| SCHEMBL290843 | 0.87 | TYR (0.42) | ENPP2INPPL1AKT1INPP5AS1PR1 | |
| SCHEMBL10350945 | 0.87 | TYR (0.42) | ENPP2INPPL1AKT1INPP5AS1PR1 | |
| SCHEMBL8958556 | 0.87 | TYR (0.42) | ENPP2INPPL1AKT1INPP5AS1PR1 | |
| SCHEMBL11128600 | 0.87 | TYR (0.42) | ENPP2INPPL1AKT1INPP5AS1PR1 | |
| SCHEMBL29892389 | 0.87 | TYR (0.42) | ENPP2INPPL1AKT1INPP5AS1PR1 | |
| SCHEMBL28046741 | 0.87 | PLK1 (0.46) | ENPP2INPPL1INPP5AS1PR1S1PR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0138599-B1 | POLYPHENYLENE ETHER RESIN COMPOSITION | MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) | 1989-03-29 | — | — | EP | disclosed |
| US-4556685-A | BLENDS, IMPACT STRENGTH, MOLDABLE | MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) | 1985-12-03 | — | — | US | disclosed |
| EP-0138599-A2 | Polyphenylene ether resin composition | MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) | 1985-04-24 | — | — | EP | disclosed |