SCHEMBL456732

SCHEMBL456732

CCCCCCCCCCCCc1c(C)ccc(OP(=O)(Oc2ccc(C)c(CCCCCCCCCCCC)c2CCCCCCCCCCCC)Oc2ccc(C)c(CCCCCCCCCCCC)c2CCCCCCCCCCCC)c1CCCCCCCCCCCC

nearest known ligand 0.44

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
ENPP2 Q13822 1/20 0.38
ALOX5 P09917 2/20 0.36
KDM4E B2RXH2 1/20 0.35
ALDH1A1 P00352 1/20 0.35
HPGD P15428 1/20 0.35
HSD17B10 Q99714 1/20 0.35
SLC2A1 P11166 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10596248 0.88 ENPP2 (0.43) ENPP2ALOX5
SCHEMBL456734 0.88 ENPP2 (0.43) ENPP2ALOX5
SCHEMBL17491577 0.86 TYR (0.41) ENPP2ALOX5ALDH1A1
SCHEMBL10350944 0.86 TYR (0.41) ENPP2ALOX5ALDH1A1
SCHEMBL11128598 0.86 TYR (0.41) ENPP2ALOX5ALDH1A1
SCHEMBL290842 0.86 TYR (0.41) ENPP2ALOX5ALDH1A1
SCHEMBL8958551 0.86 TYR (0.41) ENPP2ALOX5ALDH1A1
SCHEMBL381663 0.79 NCEH1 (0.36)
SCHEMBL28750605 0.78 PTGS2 (0.46) KDM4EALDH1A1HSD17B10
SCHEMBL9332296 0.78 PPARA (0.49) ALOX5SLC2A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 370 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20070149661-A1 POLYCARBONATE COMPOSITION, METHOD OF MANUFACTURE THEREOF AND ARTICLES COMPRISING THE SAME CITIBANK, N.A., AS COLLATERAL AGENT 2007-06-28 US claimed
US-12570848-B2 Scratch-resistant high impact strength PMMA compositions SHPP GLOBAL TECHNOLOGIES B.V. (NL) 2026-03-10 US disclosed
US-12403437-B2 Method for producing nanodiamonds doped with group 14 element, and method for purifying same DAICEL CORPORATION (JP) 2025-09-02 US disclosed
US-12351463-B2 Heteroatom-doped nanodiamond DAICEL CORPORATION (JP) 2025-07-08 US disclosed
EP-4172269-B1 THERMOPLASTIC COMPOSITIONS WITH IMPROVED HYDROLYTIC AND HEAT STABILITY SHPP GLOBAL TECH BV (NL) 2025-05-28 EP disclosed
WO-2025104593-A1 PFAS-FREE FLAME RETARDANT, IMPACT RESISTANT AND CHEMICAL RESISTANT POLYCARBONATE COMPOSITIONS SHPP GLOBAL TECHNOLOGIES B.V. (NL) 2025-05-22 WO disclosed
EP-3722354-B1 VEHICLE-MOUNTED LITHIUM ION BATTERY MEMBER ASAHI CHEMICAL IND (JP) 2025-04-23 EP disclosed
US-20250002355-A1 HETEROATOM-DOPED NANODIAMOND PARTICLES AND METHOD FOR PRODUCING HETEROATOM-DOPED NANODIAMOND PARTICLES DAICEL CORPORATION (JP) 2025-01-02 US disclosed
WO-2024219059-A1 NV CENTER-CONTAINING NANODIAMOND PARTICLE AND METHOD FOR PRODUCING SAME 株式会社ダイセル 2024-10-24 WO disclosed
EP-3390469-B1 METHOD FOR ISOMER REDUCTION DURING POLYMERIZATION AND SYSTEM FOR ACCOMPLISHING THE SAME DOW GLOBAL TECHNOLOGIES LLC (US) 2024-09-04 EP disclosed
EP-0055473-A1 Resin compositions SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1982-07-07 EP disclosed
EP-0043838-A4 POLYPHENYLENE OXIDE/PLASTICIZER/HYDROGENATED RADIAL TELEBLOCK COPOLYMER BLENDS. GEN ELECTRIC (US) 1982-04-29 EP disclosed
US-4313864-A IMPACT RESISTANCE GENERAL ELECTRIC COMPANY (US) 1982-02-02 US disclosed
EP-0043838-A1 POLYPHENYLENE OXIDE/PLASTICIZER/HYDROGENATED RADIAL TELEBLOCK COPOLYMER BLENDS GENERAL ELECTRIC COMPANY (US) 1982-01-20 EP disclosed
WO-1981002160-A1 POLYPHENYLENE OXIDE/PLASTICIZER/HYDROGENATED RADIAL TELEBLOCK COPOLYMER BLENDS GEN ELECTRIC (US) 1981-08-06 WO disclosed
US-4254011-A CONTAINING A TWO-PHASE CROSSLINKED POLYACRYLATE BAYER AKTIENGESELLSCHAFT (DE) 1981-03-03 US disclosed
US-4154712-A VINYLAROMATIC-CONJUGATED DIENE BLOCK POLYMER GENERAL ELECTRIC COMPANY (US) 1979-05-15 US disclosed
US-4136089-A 2,2-DIETHYL-PROPANE-1,3-DIOL BAYER AKTIENGESELLSCHAFT (DE) 1979-01-23 US disclosed
US-4107149-A Poly(ethylene/alkylene) terephthalates which crystallize rapidly BAYER AKTIENGESELLSCHAFT (DE) 1978-08-15 US disclosed
US-4086212-A ESTERIFICATION OR TRANSESTERIFICATION BAYER AKTIENGESELLSCHAFT (DT) 1978-04-25 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12570848-B2 Scratch-resistant high impact strength PMMA compositions PCNA, COL2A1, COL1A1 ENPP2 4081/4885ALOX5 3823/4885KDM4E 713/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.