Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 9/20 | 0.82 |
| ▸ | SMN1; SMN2 | Q16637 | 7/20 | 0.82 |
| ▸ | LMNA | P02545 | 5/20 | 0.66 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.66 |
| ▸ | MAPT | P10636 | 5/20 | 0.66 |
| ▸ | MEN1 | O00255 | 4/20 | 0.66 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.66 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.66 |
| ▸ | HPGD | P15428 | 1/20 | 0.64 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.64 |
| ▸ | NPC1 | O15118 | 4/20 | 0.64 |
| ▸ | TSHR | P16473 | 1/20 | 0.64 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.61 |
| ▸ | POLB | P06746 | 1/20 | 0.61 |
| ▸ | LDHA | P00338 | 2/20 | 0.55 |
| ▸ | HTT | P42858 | 2/20 | 0.54 |
| ▸ | TP53 | P04637 | 1/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10871541 | 0.91 | RAB9A (0.69) | RAB9ASMN1; SMN2LMNAKMT2AMAPT | |
| SCHEMBL10600068 | 0.90 | RAB9A (0.81) | RAB9ASMN1; SMN2LMNAKMT2AMAPT | |
| SCHEMBL10596177 | 0.88 | RAB9A (0.81) | RAB9ASMN1; SMN2LMNAKMT2AMAPT | |
| SCHEMBL10871205 | 0.84 | RAB9A (0.65) | RAB9ASMN1; SMN2LMNAKMT2AMAPT | |
| SCHEMBL10597936 | 0.83 | RAB9A (0.63) | RAB9ASMN1; SMN2LMNAKMT2AMAPT | |
| SCHEMBL10871696 | 0.83 | RAB9A (0.67) | RAB9ASMN1; SMN2KMT2AMAPTMEN1 | |
| SCHEMBL10872585 | 0.81 | CASP3 (0.70) | RAB9ASMN1; SMN2LMNAKMT2AMAPT | |
| SCHEMBL10873161 | 0.81 | MAPT (0.61) | RAB9ASMN1; SMN2LMNAKMT2AMAPT | |
| SCHEMBL10348171 | 0.80 | SMN1; SMN2 (0.66) | RAB9ASMN1; SMN2LMNAKMT2AMAPT | |
| SCHEMBL23932785 | 0.80 | LDHA (0.74) | RAB9ASMN1; SMN2LMNAMAPTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0138761-B1 | PROCESS FOR THE PIGMENTATION OF MACROMOLECULAR ORGANIC MATERIALS | CIBA-GEIGY AG (CH) | 1989-03-22 | — | — | EP | disclosed |
| US-4602961-A | MONOAZO BENZOTHIAZOLE DERIVATIVES | CIBA-GEIGY CORPORATION (US) | 1986-07-29 | — | — | US | disclosed |
| EP-0138761-A2 | Process for the pigmentation of macromolecular organic materials | CIBA-GEIGY AG (CH) | 1985-04-24 | — | — | EP | disclosed |