Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | HPGD | P15428 | 3/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.48 |
| ▸ | TSHR | P16473 | 2/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.48 |
| ▸ | NOS1 | P29475 | 4/20 | 0.47 |
| ▸ | AXL | P30530 | 2/20 | 0.47 |
| ▸ | IDO1 | P14902 | 3/20 | 0.44 |
| ▸ | METAP2 | P50579 | 1/20 | 0.43 |
| ▸ | TDO2 | P48775 | 1/20 | 0.41 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.41 |
| ▸ | CDK2 | P24941 | 1/20 | 0.41 |
| ▸ | CCNA1 | P78396 | 1/20 | 0.41 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29547431 | 0.84 | NOS1 (0.59) | TDP1ALDH1A1HPGDCYP3A4TSHR | |
| SCHEMBL116315 | 0.84 | NOS1 (0.59) | TDP1ALDH1A1HPGDCYP3A4TSHR | |
| Hydrochloric Acid SCHEMBL8100664 | 0.82 | NOS1 (0.57) | TDP1ALDH1A1HPGDCYP3A4TSHR | |
| SCHEMBL18398743 | 0.79 | IDO1 (0.55) | NOS1AXLIDO1METAP2TDO2 | |
| SCHEMBL10593107 | 0.78 | NOS1 (0.47) | TDP1ALDH1A1HPGDCYP3A4TSHR | |
| SCHEMBL10595712 | 0.78 | NOS1 (0.72) | NOS1AXLIDO1METAP2TDO2 | |
| SCHEMBL12321248 | 0.77 | NOS1 (0.56) | TDP1ALDH1A1HPGDNOS1AXL | |
| SCHEMBL29450787 | 0.76 | HPRT1 (0.54) | TDP1ALDH1A1CYP3A4TSHRHSD17B10 | |
| SCHEMBL27074503 | 0.76 | HPRT1 (0.54) | TDP1ALDH1A1CYP3A4TSHRHSD17B10 | |
| SCHEMBL14876644 | 0.74 | ALDH1A1 (0.87) | TDP1ALDH1A1HPGDCYP3A4TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4871653-A | DEVELOPING IN PRESENCE OF MERCAPTO POLYAZAINDENE PROMOTERS AND NUCLEATING QUATERNARY OR HYDRAZIDE-TYPE COMPOUNDS | FUJI PHOTO FILM CO., LTD. (JP) | 1989-10-03 | — | — | US | disclosed |