Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS1 | P29475 | 4/20 | 0.47 |
| ▸ | AXL | P30530 | 2/20 | 0.47 |
| ▸ | IDO1 | P14902 | 3/20 | 0.44 |
| ▸ | METAP2 | P50579 | 1/20 | 0.43 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.41 |
| ▸ | CDK2 | P24941 | 1/20 | 0.41 |
| ▸ | CCNA1 | P78396 | 1/20 | 0.41 |
| ▸ | CDK4 | P11802 | 1/20 | 0.39 |
| ▸ | CCND1 | P24385 | 1/20 | 0.39 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.39 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.39 |
| ▸ | JAK2 | O60674 | 1/20 | 0.38 |
| ▸ | JAK1 | P23458 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.38 |
| ▸ | HPGD | P15428 | 3/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL277055 | 0.84 | NOS1 (0.59) | NOS1AXLIDO1METAP2CDK2 | |
| Hydrochloric Acid SCHEMBL6647093 | 0.82 | NOS1 (0.57) | NOS1AXLIDO1METAP2CDK2 | |
| SCHEMBL10596677 | 0.78 | TDP1 (0.48) | NOS1AXLIDO1METAP2CCNA2 | |
| SCHEMBL10595712 | 0.78 | NOS1 (0.72) | NOS1AXLIDO1METAP2CCNA2 | |
| SCHEMBL12321248 | 0.77 | NOS1 (0.56) | NOS1AXLIDO1METAP2CCNA2 | |
| SCHEMBL10593960 | 0.76 | HCAR2 (0.47) | NOS1AXLIDO1METAP2CCNA2 | |
| SCHEMBL27074503 | 0.76 | HPRT1 (0.54) | NOS1AXLIDO1METAP2CDK2 | |
| SCHEMBL29450787 | 0.76 | HPRT1 (0.54) | NOS1AXLIDO1METAP2CDK2 | |
| SCHEMBL16107538 | 0.74 | IDO1 (0.65) | IDO1CDK2JAK2CYP1A2HPGD | |
| SCHEMBL10595698 | 0.74 | BRD4 (0.51) | NOS1AXLIDO1METAP2ROCK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4871653-A | DEVELOPING IN PRESENCE OF MERCAPTO POLYAZAINDENE PROMOTERS AND NUCLEATING QUATERNARY OR HYDRAZIDE-TYPE COMPOUNDS | FUJI PHOTO FILM CO., LTD. (JP) | 1989-10-03 | — | — | US | disclosed |