Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 1/20 | 0.44 |
| ▸ | AURKA | O14965 | 2/20 | 0.43 |
| ▸ | TPX2 | Q9ULW0 | 2/20 | 0.43 |
| ▸ | IKBKB | O14920 | 1/20 | 0.40 |
| ▸ | CHUK | O15111 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.39 |
| ▸ | SERPINE1 | P05121 | 1/20 | 0.38 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
| ▸ | ALPL | P05186 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | ALAD | P13716 | 1/20 | 0.37 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.36 |
| ▸ | DHODH | Q02127 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10754874 | 0.84 | KDM4E (0.42) | NOTUMIKBKBCHUKALDH1A1SERPINE1 | |
| SCHEMBL10600088 | 0.82 | KMO (0.43) | TSHRKDM4ENPC1MAPTRAB9A | |
| SCHEMBL8780719 | 0.77 | AURKA (0.50) | NOTUMAURKATPX2IKBKBCHUK | |
| SCHEMBL9616372 | 0.68 | KMT2A (0.44) | NOTUMALDH1A1CA12KDM4EMAPT | |
| SCHEMBL15511168 | 0.68 | AURKA (0.53) | NOTUMAURKATPX2IKBKBCHUK | |
| SCHEMBL10987584 | 0.65 | MAPK14 (0.50) | AURKATPX2IKBKBCHUKMAPK14 | |
| SCHEMBL4686922 | 0.65 | IKBKB (0.76) | NOTUMAURKATPX2IKBKBCHUK | |
| SCHEMBL3653849 | 0.64 | DPP4 (0.47) | ALDH1A1KDM4E | |
| SCHEMBL2041424 | 0.62 | TSHR (0.85) | ALDH1A1ALOX15TSHRKDM4ENPC1 | |
| SCHEMBL3550171 | 0.62 | DCAF1 (0.52) | NOTUMALDH1A1ALOX15MAPK14CA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0127313-B1 | THE PRODUCTION OF HAPLOID SEED, OF DOUBLED HAPLOIDS AND OF HOMOZYGOUS PLANT LINES THEREFROM | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) (FR) | 1989-07-19 | — | — | EP | claimed |