Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AURKA | O14965 | 2/20 | 0.50 |
| ▸ | TPX2 | Q9ULW0 | 2/20 | 0.50 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.49 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.47 |
| ▸ | IKBKB | O14920 | 1/20 | 0.46 |
| ▸ | CHUK | O15111 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | F7 | P08709 | 1/20 | 0.43 |
| ▸ | F3 | P13726 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | CASP1 | P29466 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2462177 | 0.82 | KDM4E (0.50) | IKBKBCHUKALOX15ALDH1A1SMN1; SMN2 | |
| SCHEMBL10596990 | 0.77 | NOTUM (0.44) | AURKATPX2MAPK14NOTUMIKBKB | |
| SCHEMBL4686922 | 0.75 | IKBKB (0.76) | AURKATPX2MAPK14NOTUMIKBKB | |
| SCHEMBL3550171 | 0.73 | DCAF1 (0.52) | MAPK14NOTUMALOX15ALDH1A1CA12 | |
| SCHEMBL3699935 | 0.73 | — | — | |
| SCHEMBL15511168 | 0.72 | AURKA (0.53) | AURKATPX2NOTUMIKBKBCHUK | |
| SCHEMBL28654625 | 0.69 | IKBKB (0.45) | NOTUMIKBKBCHUKALDH1A1SMN1; SMN2 | |
| SCHEMBL9336033 | 0.69 | ALDH1A1 (0.49) | AURKATPX2MAPK14NOTUMNPC1 | |
| SCHEMBL9519620 | 0.69 | CA12 (0.45) | MAPK14NOTUMNPC1RAB9ATSHR | |
| SCHEMBL10987584 | 0.69 | MAPK14 (0.50) | AURKATPX2MAPK14IKBKBCHUK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0783502-A1 | NEW CARBOXAMIDES WITH ANTIFUNGAL ACTIVITY | J. URIACH & CIA. S.A. (ES) | 1997-07-16 | — | — | EP | disclosed |