SCHEMBL10600243

SCHEMBL10600243

CC(=O)Nc1cccc(OCc2ccccc2Cl)c1

nearest known ligand 0.68

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RAB9A P51151 4/20 0.60
NPC1 O15118 3/20 0.60
NR4A2 P43354 2/20 0.60
SMN1; SMN2 Q16637 2/20 0.59
MAPT P10636 1/20 0.56
MAOB P27338 2/20 0.56
MAOA P21397 1/20 0.56
MEN1 O00255 2/20 0.55
KMT2A Q03164 2/20 0.55
LMNA P02545 1/20 0.55
P2RX4 Q99571 1/20 0.53
KCNJ5 P48544 1/20 0.53
KCNJ3 P48549 1/20 0.53
AHR P35869 1/20 0.52
HSD17B10 Q99714 1/20 0.51
GCK P35557 1/20 0.51
DRD2 P14416 1/20 0.50
HTR2A P28223 1/20 0.50
SPHK2 Q9NRA0 1/20 0.49
SPHK1 Q9NYA1 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10599886 0.85 MAOA (0.68) RAB9ANPC1NR4A2SMN1; SMN2MAPT
SCHEMBL10598018 0.84 RAB9A (0.59) RAB9ANPC1SMN1; SMN2MAPTMAOB
SCHEMBL11781796 0.83 KMT2A (0.55) RAB9ANPC1NR4A2SMN1; SMN2MAPT
SCHEMBL4220016 0.83 NPC1 (0.61) RAB9ANPC1NR4A2SMN1; SMN2MAPT
SCHEMBL1436066 0.82 NR4A2 (0.77) RAB9ANPC1NR4A2MAOBMAOA
SCHEMBL7829074 0.82 NPC1 (0.56) RAB9ANPC1SMN1; SMN2MEN1KMT2A
SCHEMBL10599853 0.81 MEN1 (0.79) RAB9ANPC1NR4A2SMN1; SMN2MAOB
SCHEMBL10600206 0.79 MAOB (0.70) RAB9ANPC1NR4A2SMN1; SMN2MAOB
SCHEMBL11546092 0.78 SMN1; SMN2 (0.68) RAB9ANPC1SMN1; SMN2MAPTMEN1
SCHEMBL10264545 0.77 SMN1; SMN2 (0.67) RAB9ANPC1SMN1; SMN2MAPTMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0136678-B1 HEAT SENSITIVE RECORD MATERIAL HODOGAYA CHEMICAL CO., LTD. (JP) 1989-09-13 EP claimed
US-4539577-A Heat sensitive record material HODOGAYA CHEMICAL CO., LTD. (JP) 1985-09-03 US claimed
EP-0136678-A2 Heat sensitive record material HODOGAYA CHEMICAL CO., LTD. (JP) 1985-04-10 EP claimed
EP-0136678-B1 HEAT SENSITIVE RECORD MATERIAL HODOGAYA CHEMICAL CO., LTD. (JP) 1989-09-13 EP disclosed
US-4539577-A Heat sensitive record material HODOGAYA CHEMICAL CO., LTD. (JP) 1985-09-03 US disclosed
EP-0136678-A2 Heat sensitive record material HODOGAYA CHEMICAL CO., LTD. (JP) 1985-04-10 EP disclosed