Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | LTA4H | P09960 | 1/20 | 0.48 |
| ▸ | CALM1 | P0DP23 | 1/20 | 0.43 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.42 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.42 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | SHBG | P04278 | 1/20 | 0.42 |
| ▸ | BCL2 | P10415 | 1/20 | 0.41 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.41 |
| ▸ | CNR2 | P34972 | 1/20 | 0.40 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.40 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.40 |
| ▸ | TUBB | P07437 | 1/20 | 0.40 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.40 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.40 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.40 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.40 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.40 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14193724 | 0.89 | MAPT (0.60) | MAPTCALM1SHBGTUBB4ATUBB | |
| SCHEMBL2097755 | 0.87 | LTA4H (0.53) | LTA4HCALM1PTPN1PTPN2PTPN6 | |
| SCHEMBL14468214 | 0.81 | MAPT (0.53) | MAPTSHBGTUBB4ATUBBTUBA3C | |
| SCHEMBL6947937 | 0.80 | PTPN1 (0.43) | MAPTPTPN1PTPN2PTPN6CNR2 | |
| SCHEMBL27695787 | 0.78 | MAPT (0.74) | MAPTSHBG | |
| SCHEMBL21294089 | 0.78 | SHBG (0.58) | MAPTSHBGTUBB4ATUBBTUBA3C | |
| SCHEMBL10604182 | 0.78 | SHBG (0.46) | PTPN1PTPN2PTPN6LMNASHBG | |
| SCHEMBL14223344 | 0.77 | PDE4A (0.54) | MAPTCALM1SHBGTUBB4ATUBB | |
| SCHEMBL11720419 | 0.77 | SHBG (0.57) | CALM1PTPN1PTPN2PTPN6SHBG | |
| SCHEMBL11057543 | 0.76 | SHBG (0.44) | LTA4HPTPN1PTPN2PTPN6LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0212482-B1 | PROCESS FOR OBTAINING NEGATIVE IMAGES FROM POSITIVE PHOTORESISTS | HOECHST CELANESE CORPORATION (US) | 1989-04-19 | — | — | EP | disclosed |
| EP-0212482-A2 | Process for obtaining negative images from positive photoresists | HOECHST CELANESE CORPORATION (US) | 1987-03-04 | — | — | EP | disclosed |