SCHEMBL21294089

SCHEMBL21294089

COc1c(C)cc(Cc2cc(C)c(OC)c(CO)c2)cc1CO

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SHBG P04278 1/20 0.58
MAPT P10636 1/20 0.53
DHFR P00374 2/20 0.44
PDE4A P27815 3/20 0.40
PDE4B Q07343 3/20 0.40
PDE4C Q08493 3/20 0.40
PDE4D Q08499 3/20 0.40
PDE5A O76074 2/20 0.40
PDE1A P54750 2/20 0.40
PDE1B Q01064 2/20 0.40
PDE3B Q13370 2/20 0.40
PDE1C Q14123 2/20 0.40
PDE3A Q14432 2/20 0.40
TUBB4A P04350 1/20 0.38
TUBB P07437 1/20 0.38
TUBA3C P0DPH7 1/20 0.38
TUBA1B P68363 1/20 0.38
TUBA4A P68366 1/20 0.38
TUBB4B P68371 1/20 0.38
TUBB3 Q13509 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14193724 0.88 MAPT (0.60) SHBGMAPTDHFRPDE4APDE4B
SCHEMBL13304653 0.81 DHFR (0.51) SHBGDHFRTUBB4ATUBBTUBA3C
SCHEMBL14468214 0.81 MAPT (0.53) SHBGMAPTDHFRPDE4APDE4B
SCHEMBL20362610 0.80 MAPT (0.47) SHBGMAPTPDE4APDE4BPDE4C
SCHEMBL10734341 0.78 MAPT (0.46) MAPTPDE4APDE4BPDE4CPDE4D
SCHEMBL10600372 0.78 MAPT (0.50) SHBGMAPTTUBB4ATUBBTUBA3C
SCHEMBL2620577 0.78 PDE4A (0.40) SHBGMAPTDHFRPDE4APDE4B
SCHEMBL27695787 0.77 MAPT (0.74) SHBGMAPTPDE4APDE4BPDE4C
SCHEMBL7088043 0.77 MAPT (0.52) SHBGMAPTDHFRPDE4APDE4B
SCHEMBL24458095 0.77 MAPT (0.44) MAPTPDE4APDE4BPDE4CPDE4D

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10920017-B2 Polyimide resin and resin composition KANEKA CORPORATION (JP) 2021-02-16 US disclosed
US-20190263968-A1 POLYIMIDE RESIN AND RESIN COMPOSITION KANEKA CORPORATION (JP) 2019-08-29 US disclosed