Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | CASP3 | P42574 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.36 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.36 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3624284 | 0.80 | TSHR (0.43) | ALDH1A1TSHR | |
| SCHEMBL536089 | 0.79 | ALDH1A1 (0.44) | ATMALDH1A1TSHRTDP1 | |
| SCHEMBL779788 | 0.78 | MAPK1 (0.41) | NPC1LMNAMAPK1CASP3RAB9A | |
| SCHEMBL9248714 | 0.77 | ALDH1A1 (0.33) | ALDH1A1TSHRTDP1 | |
| SCHEMBL8103470 | 0.76 | CYP3A4 (0.46) | NPC1LMNAMAPK1CASP3RAB9A | |
| SCHEMBL8760881 | 0.76 | MAPK1 (0.44) | NPC1LMNAMAPK1CASP3RAB9A | |
| SCHEMBL7292118 | 0.75 | ALDH1A1 (0.32) | ALDH1A1TSHRTDP1 | |
| SCHEMBL11806035 | 0.72 | GABRA1 (0.44) | NPC1LMNAMAPK1CASP3RAB9A | |
| SCHEMBL1535124 | 0.72 | MAPK1 (0.39) | NPC1LMNAMAPK1CASP3RAB9A | |
| SCHEMBL29260335 | 0.72 | NPC1 (0.37) | NPC1LMNAMAPK1CASP3RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0248423-B1 | PROCESS OR THE ACYLATION OF AROMATIC COMPOUNDS | BASF Aktiengesellschaft (DE) | 1989-08-30 | — | — | EP | disclosed |
| EP-0248423-A1 | Process or the acylation of aromatic compounds | BASF Aktiengesellschaft (DE) | 1987-12-09 | — | — | EP | disclosed |