Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | VCAM1 | P19320 | 5/20 | 0.37 |
| ▸ | GPR35 | Q9HC97 | 2/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.35 |
| ▸ | TXNRD1 | Q16881 | 1/20 | 0.35 |
| ▸ | TXNRD3 | Q86VQ6 | 1/20 | 0.35 |
| ▸ | TXNRD2 | Q9NNW7 | 1/20 | 0.35 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.33 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | KDM4A | O75164 | 1/20 | 0.33 |
| ▸ | KDM4B | O94953 | 1/20 | 0.33 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8932007 | 0.87 | GPR35 (0.43) | TDP1TSHRALDH1A1MAPK1VCAM1 | |
| SCHEMBL9251185 | 0.80 | GPR35 (0.51) | TDP1ALDH1A1MAPK1GPR35CYP3A4 | |
| SCHEMBL10597548 | 0.77 | TDP1 (0.46) | TDP1TSHRALDH1A1MAPK1VCAM1 | |
| SCHEMBL31503783 | 0.74 | GPR35 (0.43) | TDP1ALDH1A1VCAM1GPR35CYP3A4 | |
| SCHEMBL10600459 | 0.73 | TSHR (0.42) | TSHRALDH1A1MAPK1MAPT | |
| SCHEMBL3650611 | 0.72 | TDP1 (0.61) | TDP1TSHRALDH1A1MAPK1VCAM1 | |
| SCHEMBL29939725 | 0.72 | TDP1 (0.61) | TDP1TSHRALDH1A1MAPK1VCAM1 | |
| SCHEMBL9282606 | 0.71 | TSHR (0.42) | TDP1TSHRALDH1A1MAPK1VCAM1 | |
| SCHEMBL8506870 | 0.71 | TDP1 (0.38) | TDP1TSHRALDH1A1GPR35CYP3A4 | |
| SCHEMBL14810031 | 0.71 | TSHR (0.37) | TSHRALDH1A1MAPK1VCAM1GPR35 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0175151-B1 | 2,4-DICHLORO-3-ALKYL-6-NITROPHENOLS AND PROCESS FOR THEIR PREPARATION | BAYER AG (DE) | 1989-01-18 | — | — | EP | claimed |
| US-4670608-A | CATALYTIC CHLORINATION OF 1-ALKYL-4-NITROBENZENE | BAYER AKTIENGESELLSCHAFT (DE) | 1987-06-02 | — | — | US | disclosed |
| US-4670608-A | CATALYTIC CHLORINATION OF 1-ALKYL-4-NITROBENZENE | BAYER AKTIENGESELLSCHAFT (DE) | 1987-06-02 | — | — | US | disclosed |