Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.61 |
| ▸ | GPR35 | Q9HC97 | 2/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.54 |
| ▸ | TSHR | P16473 | 4/20 | 0.54 |
| ▸ | VCAM1 | P19320 | 5/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.50 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.50 |
| ▸ | TXNRD1 | Q16881 | 1/20 | 0.50 |
| ▸ | TXNRD3 | Q86VQ6 | 1/20 | 0.50 |
| ▸ | TXNRD2 | Q9NNW7 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3650611 | 1.00 | TDP1 (0.61) | TDP1GPR35ALDH1A1TSHRVCAM1 | |
| SCHEMBL8654568 | 0.87 | GPR35 (0.71) | TDP1GPR35ALDH1A1TSHRVCAM1 | |
| SCHEMBL5579130 | 0.82 | TSHR (0.75) | TDP1GPR35ALDH1A1TSHRVCAM1 | |
| SCHEMBL9194645 | 0.82 | TSHR (0.61) | TDP1GPR35ALDH1A1TSHRVCAM1 | |
| SCHEMBL28734210 | 0.82 | ALDH1A1 (0.56) | TDP1GPR35ALDH1A1TSHRVCAM1 | |
| SCHEMBL31053019 | 0.80 | GPR35 (0.74) | TDP1GPR35ALDH1A1TSHRCYP3A4 | |
| SCHEMBL1192005 | 0.80 | ALDH1A1 (0.50) | TDP1GPR35ALDH1A1TSHRVCAM1 | |
| SCHEMBL8653908 | 0.80 | ALDH1A1 (0.50) | TDP1GPR35ALDH1A1TSHRVCAM1 | |
| SCHEMBL28904818 | 0.80 | TDP1 (0.50) | TDP1GPR35ALDH1A1TSHRVCAM1 | |
| SCHEMBL9226136 | 0.80 | GPR35 (0.74) | TDP1GPR35ALDH1A1TSHRVCAM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118955296-A | Method for preparing 2, 4-difluoroaniline and 2,3, 4-trifluoroaniline by using 3, 4-dichloronitrobenzene as raw material | 山东国邦药业有限公司 | 2024-11-15 | — | — | CN | claimed |
| CN-118955296-A | Method for preparing 2, 4-difluoroaniline and 2,3, 4-trifluoroaniline by using 3, 4-dichloronitrobenzene as raw material | 山东国邦药业有限公司 | 2024-11-15 | — | — | CN | disclosed |
| CN-118955296-A | Method for preparing 2, 4-difluoroaniline and 2,3, 4-trifluoroaniline by using 3, 4-dichloronitrobenzene as raw material | 山东国邦药业有限公司 | 2024-11-15 | — | — | CN | disclosed |
| CN-117202924-A | Therapeutic regimens and methods for lowering blood glucose and/or body weight using GLP-1R and GCGR balance agonists | 斯皮特弗尔制药有限责任公司 | 2023-12-08 | — | — | CN | disclosed |
| EP-3802754-B1 | ASSOCIATIVE AND EXCHANGEABLE OLIGOMERS, AND COMPOSITION COMPRISING SAME | TOTALENERGIES ONETECH (FR) | 2023-07-05 | — | — | EP | disclosed |
| EP-3802696-B1 | ASSOCIATIVE AND EXCHANGEABLE OLIGOMERS, COMPOSITION COMPRISING THEM | TOTALENERGIES ONETECH (FR) | 2023-07-05 | — | — | EP | disclosed |
| EP-3802755-B1 | ASSOCIATIVE AND EXCHANGEABLE OLIGOMERS, AND COMPOSITION CONTAINING SAME | TOTALENERGIES ONETECH (FR) | 2023-07-05 | — | — | EP | disclosed |
| CN-110642720-B | Preparation method of 2, 4-difluoro-3, 5-dichloronitrobenzene | 浙江吉泰新材料股份有限公司 | 2022-09-27 | — | — | CN | disclosed |