Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP17A1 | P05093 | 2/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.35 |
| ▸ | RORC | P51449 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.33 |
| ▸ | HTR2A | P28223 | 1/20 | 0.33 |
| ▸ | HTR2C | P28335 | 1/20 | 0.33 |
| ▸ | HTR2B | P41595 | 1/20 | 0.33 |
| ▸ | ABL1 | P00519 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP2E1 | P05181 | 1/20 | 0.32 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | HPGDS | O60760 | 1/20 | 0.32 |
| ▸ | LRRK2 | Q5S007 | 6/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10603126 | 0.91 | NR3C1 (0.35) | CYP17A1CYP2C9CYP2C19CYP3A4ABL1 | |
| SCHEMBL10602397 | 0.88 | ATP4A (0.35) | HTR2AHTR2CHTR2BATP4AATP4B | |
| SCHEMBL10597717 | 0.86 | PDE10A (0.38) | CYP2C9CYP3A4CYP1A2ALDH1A1GAA | |
| SCHEMBL10599937 | 0.81 | CYP17A1 (0.40) | CYP17A1CYP2C9CYP2C19HTR2AHTR2C | |
| SCHEMBL10619578 | 0.80 | PDE10A (0.37) | CYP2C9CYP3A4CYP1A2ALDH1A1GAA | |
| SCHEMBL10602392 | 0.79 | ATP4A (0.33) | ATP4AATP4B | |
| SCHEMBL10601241 | 0.77 | GPR3 (0.36) | CYP2C9CYP3A4CYP1A2GAACACNA1H | |
| SCHEMBL10621858 | 0.76 | PDE10A (0.39) | CYP2C9CYP3A4CYP1A2ALDH1A1GAA | |
| SCHEMBL10598423 | 0.76 | KCNH2 (0.30) | — | |
| SCHEMBL10603073 | 0.75 | KCNH2 (0.38) | KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4778511-A | FOR PLANTS AND MATERIALS | BAYER AKTIENGESELLSCHAFT (DE) | 1988-10-18 | — | — | US | claimed |
| EP-0195238-B1 | N-SULPHENYLIZED INDAZOLES CONTAINING FLUORINE, PROCESS FOR THEIR PREPARATION AND THEIR USE | BAYER AG (DE) | 1989-03-29 | — | — | EP | disclosed |
| US-4778511-A | FOR PLANTS AND MATERIALS | BAYER AKTIENGESELLSCHAFT (DE) | 1988-10-18 | — | — | US | disclosed |
| EP-0195238-A1 | N-sulphenylized indazoles containing fluorine, process for their preparation and their use | BAYER AG (DE) | 1986-09-24 | — | — | EP | disclosed |