Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PGR | P06401 | 5/20 | 0.50 |
| ▸ | AR | P10275 | 4/20 | 0.50 |
| ▸ | ESR1 | P03372 | 2/20 | 0.49 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.49 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.49 |
| ▸ | ACHE | P22303 | 1/20 | 0.49 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.47 |
| ▸ | ABCB11 | O95342 | 2/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.47 |
| ▸ | SHBG | P04278 | 1/20 | 0.47 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.47 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.45 |
| ▸ | STS | P08842 | 1/20 | 0.44 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11857435 | 0.87 | PGR (0.55) | PGRARESR1SLC6A4CYP2C19 | |
| SCHEMBL11857444 | 0.87 | PGR (0.55) | PGRARESR1SLC6A4CYP2C19 | |
| SCHEMBL11861768 | 0.87 | PGR (0.55) | PGRARESR1SLC6A4CYP2C19 | |
| SCHEMBL11861765 | 0.87 | PGR (0.55) | PGRARESR1SLC6A4CYP2C19 | |
| SCHEMBL6008256 | 0.86 | PGR (0.51) | PGRARESR1SLC6A4CYP2C19 | |
| SCHEMBL11788940 | 0.84 | LMNA (0.69) | PGRARESR1SLC6A4CYP2C19 | |
| SCHEMBL10603383 | 0.84 | LMNA (0.69) | PGRARESR1SLC6A4CYP2C19 | |
| SCHEMBL9472235 | 0.83 | LMNA (0.62) | PGRARESR1SLC6A4CYP2C19 | |
| SCHEMBL7882963 | 0.83 | LMNA (0.62) | PGRARESR1SLC6A4CYP2C19 | |
| Norethandrolone SCHEMBL23801611 | 0.81 | LMNA (0.71) | PGRARESR1SLC6A4CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0159739-B1 | STEROIDS FOR USE AS IMMUNOMODULATORS | AKZO N.V. (NL) | 1989-05-10 | — | — | EP | disclosed |