Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PGR | P06401 | 5/20 | 0.51 |
| ▸ | SHBG | P04278 | 3/20 | 0.51 |
| ▸ | NR3C1 | P04150 | 3/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.51 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.51 |
| ▸ | HTR2B | P41595 | 1/20 | 0.51 |
| ▸ | AR | P10275 | 3/20 | 0.51 |
| ▸ | LMNA | P02545 | 4/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.48 |
| ▸ | ABCB11 | O95342 | 2/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.48 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | ESR1 | P03372 | 1/20 | 0.48 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.48 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10601034 | 0.86 | PGR (0.50) | PGRSHBGNR3C1ALDH1A1AR | |
| SCHEMBL7882963 | 0.86 | LMNA (0.62) | PGRSHBGNR3C1ALDH1A1AR | |
| SCHEMBL9472235 | 0.86 | LMNA (0.62) | PGRSHBGNR3C1ALDH1A1AR | |
| SCHEMBL11788940 | 0.85 | LMNA (0.69) | PGRSHBGNR3C1ALDH1A1ADRA1A | |
| SCHEMBL10603383 | 0.85 | LMNA (0.69) | PGRSHBGNR3C1ALDH1A1ADRA1A | |
| SCHEMBL13334668 | 0.83 | PGR (0.46) | PGRSHBGNR3C1ALDH1A1ADRA1A | |
| SCHEMBL9322215 | 0.82 | PGR (0.46) | PGRSHBGNR3C1ALDH1A1AR | |
| SCHEMBL7084017 | 0.82 | SHBG (0.42) | PGRSHBGNR3C1ALDH1A1ADRA1A | |
| SCHEMBL6512260 | 0.82 | ALDH1A1 (0.46) | PGRSHBGNR3C1ALDH1A1ADRA1A | |
| SCHEMBL8425073 | 0.82 | PGR (0.49) | PGRSHBGNR3C1ALDH1A1AR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0941039-A4 | TRANSDERMAL ADMINISTRATION OF MENT | POPULATION COUNCIL INC (US) | 2006-06-21 | — | — | EP | disclosed |
| US-7018648-B2 | Transdermal device for administering testosterone or one of the derivatives thereof | PIERRE FABRE MEDICAMENT (FR) | 2006-03-28 | — | — | US | disclosed |
| US-20050256051-A1 | Nuclear receptor-mediated introduction of a PNA into cell nuclei | THE POPULATION COUNCIL, INC. (US) | 2005-11-17 | — | — | US | disclosed |
| US-20050100586-A1 | Transdermal device for administering testosterone or one of the derivatives thereof | PIERRE FABRE MEDICAMENT (FR) | 2005-05-12 | — | — | US | disclosed |
| EP-0966288-A4 | ANDROGEN AS A MALE CONTRACEPTIVE AND NON-CONTRACEPTIVE ANDROGEN REPLACEMENT | POPULATION COUNCIL INC (US) | 2004-11-10 | — | — | EP | disclosed |
| EP-1178806-B1 | TRANSDERMAL DEVICE FOR THE APPLICATION OF TESTOSTERONE OR ONE OF THE DERIVATIVES THEREOF | PF MEDICAMENT (FR) | 2004-09-01 | — | — | EP | disclosed |
| US-6767902-B2 | Androgen as a male contraceptive and non-contraceptive androgen replacement | THE POPULATION COUNCIL, INC. | 2004-07-27 | — | — | US | disclosed |
| US-20040132698-A1 | Androgen as a male contraceptive and non-contraceptive androgen replacement | MOO-YOUNG ALFRED J (US) | 2004-07-08 | — | — | US | disclosed |
| US-20040126418-A1 | Transdermal administration of MENT | THE POPULATION COUNCIL, INC. | 2004-07-01 | — | — | US | disclosed |
| WO-2003068314-A1 | PULMONARY ADMINISTRATION OF 6-ALPHA-ALKYLATED TESTOSTERONE DERIVATIVES FOR ANDROGEN REPLACEMENT THERAPY | PANTARHEI BIOSCIENCE B.V. (NL) | 2003-08-21 | — | — | WO | disclosed |
| US-20030096739-A1 | Nuclear receptor-mediated introduction of a PNA into cell nuclei | POPULATION COUNCIL, INC., THE | 2003-05-22 | — | — | US | disclosed |
| US-20020193359-A1 | Administering to a non-sterile male subject a predetermined amount of an androgen which is sufficient to render male subject reversibly sterile for a predetermined period of time | POPULATION COUNCIL, INC., THE | 2002-12-19 | — | — | US | disclosed |
| EP-1178806-A1 | TRANSDERMAL DEVICE FOR THE APPLICATION OF TESTOSTERONE OR ONE OF THE DERIVATIVES THEREOF | PIERRE FABRE MEDICAMENT (FR) | 2002-02-13 | — | — | EP | disclosed |
| US-20020012694-A1 | TRANSDERMAL ADMINISTRATION OF MENT | POPULATION COUNCIL, INC., THE, A CORP. OF NY | 2002-01-31 | — | — | US | disclosed |
| WO-2000071133-A1 | TRANSDERMAL DEVICE FOR THE APPLICATION OF TESTOSTERONE OR ONE OF THE DERIVATIVES THEREOF | PIERRE FABRE MEDICAMENT (FR) | 2000-11-30 | — | — | WO | disclosed |
| EP-0966288-A1 | ANDROGEN AS A MALE CONTRACEPTIVE AND NON-CONTRACEPTIVE ANDROGEN REPLACEMENT | THE POPULATION COUNCIL, INC. (US) | 1999-12-29 | — | — | EP | disclosed |
| EP-0941039-A1 | TRANSDERMAL ADMINISTRATION OF MENT | THE POPULATION COUNCIL, INC. (US) | 1999-09-15 | — | — | EP | disclosed |
| WO-1999013812-A1 | TRANSDERMAL ADMINISTRATION OF MENT | THE POPULATION COUNCIL, INC. (US) | 1999-03-25 | — | — | WO | disclosed |
| WO-1999013883-A1 | ANDROGEN AS A MALE CONTRACEPTIVE AND NON-CONTRACEPTIVE ANDROGEN REPLACEMENT | THE POPULATION COUNCIL, INC. (US) | 1999-03-25 | — | — | WO | disclosed |
| US-5342834-A | Administering testosterone derivatives | THE POPULATION COUNCIL, INC. (US) | 1994-08-30 | — | — | US | disclosed |