Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.32 |
| ▸ | USP2 | O75604 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 2/20 | 0.31 |
| ▸ | ZDHHC20 | Q5W0Z9 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | THRB | P10828 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | CES1 | P23141 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2864684 | 0.86 | TSHR (0.46) | TSHR | |
| SCHEMBL19809187 | 0.80 | THRB (0.35) | TSHRHTTMEN1THRBKMT2A | |
| SCHEMBL708500 | 0.80 | THRB (0.35) | TSHRHTTMEN1THRBKMT2A | |
| SCHEMBL703902 | 0.80 | THRB (0.35) | TSHRHTTMEN1THRBKMT2A | |
| SCHEMBL235281 | 0.78 | TSHR (0.44) | TSHRMEN1KMT2A | |
| SCHEMBL11332079 | 0.78 | TSHR (0.40) | TSHRHTTMEN1THRBKMT2A | |
| SCHEMBL5575092 | 0.78 | TSHR (0.40) | TSHRHTTMEN1THRBKMT2A | |
| SCHEMBL5572088 | 0.78 | TSHR (0.40) | TSHRHTTMEN1THRBKMT2A | |
| SCHEMBL705136 | 0.77 | THRB (0.37) | TSHRHTTMEN1THRBKMT2A | |
| SCHEMBL1609565 | 0.75 | THRB (0.35) | TSHRHTTMEN1THRBKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0167887-B1 | PROCESS FOR THE PREPARATION OF N-SUBSTITUTED AMINOALKYLSILANES | UNION CARBIDE CORPORATION (US) | 1989-01-25 | — | — | EP | disclosed |
| EP-0167887-A1 | Process for the preparation of N-substituted aminoalkylsilanes | UNION CARBIDE CORPORATION (US) | 1986-01-15 | — | — | EP | disclosed |
| US-4526996-A | Reacting primary or secondary amine with cyanoalkylsilane in the presence of rhodium, platinum, palladium hydrogenation catalyst | UNION CARBIDE CORPORATION (US) | 1985-07-02 | — | — | US | disclosed |