Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PGR | P06401 | 5/20 | 0.70 |
| ▸ | AR | P10275 | 5/20 | 0.70 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.70 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.66 |
| ▸ | NR3C1 | P04150 | 4/20 | 0.66 |
| ▸ | LMNA | P02545 | 3/20 | 0.66 |
| ▸ | MEN1 | O00255 | 3/20 | 0.66 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.66 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.66 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.66 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.66 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.66 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.66 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.66 |
| ▸ | POLB | P06746 | 1/20 | 0.66 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.59 |
| ▸ | CYP19A1 | P11511 | 7/20 | 0.58 |
| ▸ | THRB | P10828 | 2/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Medrogestone SCHEMBL1650494 | 0.84 | PGR (0.78) | PGRARCHRM1SMN1; SMN2NR3C1 | |
| Medrogestone SCHEMBL13575809 | 0.84 | PGR (0.78) | PGRARCHRM1SMN1; SMN2NR3C1 | |
| Medrogestone SCHEMBL140614 | 0.84 | PGR (0.78) | PGRARCHRM1SMN1; SMN2NR3C1 | |
| SCHEMBL2294866 | 0.83 | PGR (1.00) | PGRARCHRM1SMN1; SMN2NR3C1 | |
| SCHEMBL5020044 | 0.83 | PGR (1.00) | PGRARCHRM1SMN1; SMN2NR3C1 | |
| SCHEMBL16690685 | 0.83 | PGR (1.00) | PGRARCHRM1SMN1; SMN2NR3C1 | |
| SCHEMBL8942 | 0.83 | PGR (1.00) | PGRARCHRM1SMN1; SMN2NR3C1 | |
| Acetic Acid SCHEMBL25192781 | 0.81 | PGR (0.96) | PGRARCHRM1SMN1; SMN2NR3C1 | |
| Acetic Acid SCHEMBL28104035 | 0.80 | PGR (0.94) | PGRARCHRM1SMN1; SMN2NR3C1 | |
| Megestrol Acetate SCHEMBL190902 | 0.79 | AR (1.00) | PGRARCHRM1SMN1; SMN2NR3C1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0152429-B1 | PROGESTATIONALLY ACTIVE STEROIDS | RESEARCH TRIANGLE INSTITUTE (US) | 1989-10-11 | — | — | EP | claimed |
| EP-0152429-A4 | PROGESTATIONALLY ACTIVE STEROIDS. | RES TRIANGLE INST (US) | 1985-12-05 | — | — | EP | claimed |
| EP-0152429-A1 | PROGESTATIONALLY ACTIVE STEROIDS. | RES TRIANGLE INST (US) | 1985-08-28 | — | — | EP | claimed |
| US-4512986-A | FERTILITY CONTROL | RESEARCH TRIANGLE INSTITUTE (US) | 1985-04-23 | — | — | US | claimed |
| WO-1985000609-A1 | PROGESTATIONALLY ACTIVE STEROIDS | RESEARCH TRIANGLE INSTITUTE (US) | 1985-02-14 | — | — | WO | claimed |
| EP-0152429-B1 | PROGESTATIONALLY ACTIVE STEROIDS | RESEARCH TRIANGLE INSTITUTE (US) | 1989-10-11 | — | — | EP | disclosed |
| EP-0152429-A4 | PROGESTATIONALLY ACTIVE STEROIDS. | RES TRIANGLE INST (US) | 1985-12-05 | — | — | EP | disclosed |
| EP-0152429-A1 | PROGESTATIONALLY ACTIVE STEROIDS. | RES TRIANGLE INST (US) | 1985-08-28 | — | — | EP | disclosed |
| US-4512986-A | FERTILITY CONTROL | RESEARCH TRIANGLE INSTITUTE (US) | 1985-04-23 | — | — | US | disclosed |
| WO-1985000609-A1 | PROGESTATIONALLY ACTIVE STEROIDS | RESEARCH TRIANGLE INSTITUTE (US) | 1985-02-14 | — | — | WO | disclosed |