Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | GPR3 | P46089 | 1/20 | 0.36 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.35 |
| ▸ | RORC | P51449 | 1/20 | 0.35 |
| ▸ | SOS1 | Q07889 | 1/20 | 0.33 |
| ▸ | HSPB1 | P04792 | 1/20 | 0.33 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.33 |
| ▸ | MAOB | P27338 | 4/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | APP | P05067 | 1/20 | 0.32 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | CA7 | P43166 | 1/20 | 0.32 |
| ▸ | CA9 | Q16790 | 1/20 | 0.32 |
| ▸ | ACHE | P22303 | 1/20 | 0.32 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10709647 | 0.82 | MAPT (0.47) | GAAGPR3MAOBMAPTEPHX2 | |
| SCHEMBL255560 | 0.79 | GPR3 (0.52) | GAAGPR3HSD11B1MAOBMAPT | |
| SCHEMBL75387 | 0.78 | ESR2 (0.46) | MAPTCA1CA2CA9 | |
| SCHEMBL1119553 | 0.78 | MAPT (0.31) | MAPTEPHX2 | |
| SCHEMBL1259588 | 0.78 | TRPV1 (0.42) | MAPTAPPEPHX2CA1CA2 | |
| SCHEMBL8650371 | 0.78 | CA1 (0.45) | MAOBCA1CA2CA9 | |
| SCHEMBL2090918 | 0.78 | MAPT (0.31) | MAPTEPHX2 | |
| SCHEMBL9476043 | 0.78 | ALDH1A1 (0.46) | GAAMAOBMAPT | |
| SCHEMBL7931525 | 0.78 | PPARA (0.44) | MAOBMAPTCA1CA2CA9 | |
| SCHEMBL2088463 | 0.78 | EPHX2 (0.35) | GAAMAPTEPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0199660-B1 | PROCESS FOR THE PREPARATION OF AROMATIC 1,1-DIFLUOROPERHALOALKOXY OR 1,1-DIFLUOROPERHALOTHIOALKYL DERIVATIVES | RHONE-POULENC CHIMIE (FR) | 1989-02-08 | — | — | EP | disclosed |
| US-4727187-A | CATALYTIC FLUORINATION OF DICHLOROALKYL PHENYL ETHER | CIBA-GEIGY CORPORATION (US) | 1988-02-23 | — | — | US | disclosed |
| US-4695657-A | Process for preparing compounds containing a difluoromethylene group in a position α to an oxygen atom | RHONE-POULENC SPECIALITES CHIMIQUES (FR) | 1987-09-22 | — | — | US | disclosed |
| US-4668830-A | Process for the preparation of compounds containing a difluoromethylene or trifluoromethyl group | RHONE-POULENC SPECIALITES CHIMIQUES (FR) | 1987-05-26 | — | — | US | disclosed |
| EP-0199660-A1 | Process for the preparation of aromatic 1,1-difluoroperhaloalkoxy or 1,1-difluoroperhalothioalkyl derivatives | RHONE-POULENC CHIMIE (FR) | 1986-10-29 | — | — | EP | disclosed |