SCHEMBL255560

SCHEMBL255560

Fc1ccc(OC(F)(F)F)cc1

nearest known ligand 0.52

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
GPR3 P46089 3/20 0.52
GAA P10253 1/20 0.48
MAPT P10636 2/20 0.48
EPHX2 P34913 2/20 0.48
HSD11B1 P28845 1/20 0.45
L3MBTL1 Q9Y468 1/20 0.42
KDM4E B2RXH2 1/20 0.42
CHRNA7 P36544 1/20 0.42
CASR P41180 1/20 0.42
SLC6A2 P23975 1/20 0.42
SLC6A4 P31645 1/20 0.42
SLC6A3 Q01959 1/20 0.42
KIF11 P52732 1/20 0.41
PDE2A O00408 1/20 0.41
NISCH Q9Y2I1 1/20 0.41
MAOB P27338 1/20 0.40
AOC3 Q16853 1/20 0.40
ALDH1A1 P00352 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7937983 0.93 GPR3 (0.47) GPR3GAAMAPTEPHX2HSD11B1
SCHEMBL7938385 0.93 KIF11 (0.50) GPR3GAAMAPTEPHX2HSD11B1
SCHEMBL254957 0.88 MAPT (0.56) GPR3GAAMAPTEPHX2L3MBTL1
SCHEMBL7929139 0.87 SLC6A4 (0.50) GPR3GAAMAPTL3MBTL1CASR
SCHEMBL7940692 0.87 CHRNA7 (0.52) GPR3GAAMAPTEPHX2HSD11B1
SCHEMBL7940638 0.85 TRPV1 (0.44) GPR3GAAMAPTEPHX2HSD11B1
SCHEMBL7929077 0.85 ESR1 (0.43) GPR3GAAMAPTEPHX2HSD11B1
SCHEMBL7937431 0.83 HSD11B1 (0.49) GAAHSD11B1KIF11
SCHEMBL12204657 0.83 PDE2A (0.51) GPR3GAAMAPTEPHX2HSD11B1
SCHEMBL7929195 0.83 NPC1 (0.54) GAAEPHX2HSD11B1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 232 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117239230-B Lithium ion battery electrolyte additive, lithium ion battery electrolyte and preparation method of lithium ion battery electrolyte additive 哈尔滨工业大学 2024-06-04 CN claimed
CN-117239230-A Lithium ion battery electrolyte additive, lithium ion battery electrolyte and preparation method of lithium ion battery electrolyte additive 哈尔滨工业大学 2023-12-15 CN claimed
CN-116864809-A Lithium ion battery electrolyte and application thereof 远景动力技术(江苏)有限公司 2023-10-10 CN claimed
US-20210079534-A1 METHOD, CELL, AND ELECTROLYTE FOR DINITROGEN CONVERSION MONASH UNIVERSITY (AU) 2021-03-18 US claimed
EP-3658505-A1 METHOD, CELL AND ELECTROLYTE FOR DINITROGEN CONVERSION Monash University (AU) 2020-06-03 EP claimed
CN-110869319-A Method for dinitrogen conversion, battery and electrolyte 莫纳什大学 2020-03-06 CN claimed
WO-2012054782-A2 FLUOROALKOXYLATION OF ORGANIC COMPOUNDS PRESIDENTS AND FELLOWS OF HARVARD COLLEGE (US) 2012-04-26 WO claimed
CN-117239230-B Lithium ion battery electrolyte additive, lithium ion battery electrolyte and preparation method of lithium ion battery electrolyte additive 哈尔滨工业大学 2024-06-04 CN disclosed
CN-117720550-A Synthesis method of (S) -3-methyl-4-oxo-2-oxa-8-azaspiro [4.5] decane-8-carboxylic acid tert-butyl ester 深圳市华先医药科技有限公司 2024-03-19 CN disclosed
CN-117239230-A Lithium ion battery electrolyte additive, lithium ion battery electrolyte and preparation method of lithium ion battery electrolyte additive 哈尔滨工业大学 2023-12-15 CN disclosed
US-20230346753-A1 NOVEL COMPOUNDS AND COMPOSITIONS FOR THE INHIBITION OF NAMPT VALO HEALTH, INC. 2023-11-02 US disclosed
WO-2023196254-A1 ALUMINUM-ETHER-BASED COMPOSITION FOR BATTERIES AND AMBIENT TEMPERATURE ALUMINUM DEPOSITION BATTELLE MEMORIAL INSTITUTE (US) 2023-10-12 WO disclosed
EP-3788038-B1 KRAS G12C INHIBITORS AND METHODS OF USING THE SAME AMGEN INC (US) 2023-10-11 EP disclosed
EP-0802173-A1 Process for producing heterocylic aromatic amine or arylamine Tosoh Corporation (JP) 1997-10-22 EP disclosed
EP-0315862-B1 Aromatically fluorinated fluoromethoxy- and fluoromethylthio-amino benzenes and their preparation BAYER AG (DE) 1994-04-13 EP disclosed
EP-0318704-B1 3-CYANO-4-PHENYL-PYRROLE DERIVATIVES BAYER AG (DE) 1992-12-02 EP disclosed
US-5015757-A Fungicides BAYER AKTIENGESELLSCHAFT (DE) 1991-05-14 US disclosed
US-4960789-A FUNGICIDES BAYER AKTIENGESELLSCHAFT (DE) 1990-10-02 US disclosed
EP-0315862-A2 Aromatically fluorinated fluoromethoxy- and fluoromethylthio-amino benzenes and their preparation BAYER AG (DE) 1989-05-17 EP disclosed
EP-0273409-A1 Nitrohaloalkoxybenzenes, processes for their preparation and their use HOECHST AKTIENGESELLSCHAFT (DE) 1988-07-06 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230346753-A1 NOVEL COMPOUNDS AND COMPOSITIONS FOR THE INHIBITION OF NAMPT NAMPT, NNMT, NQO1 GPR3 2010/4885GAA 624/4885MAPT 519/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.