SCHEMBL1060360

SCHEMBL1060360

CCOC(=O)CCCCCP(=O)(O)O

nearest known ligand 0.52

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
LPAR3 Q9UBY5 4/20 0.52
LPAR2 Q9HBW0 2/20 0.52
CYP1A2 P05177 1/20 0.52
ALDH1A1 P00352 1/20 0.47
CYP3A4 P08684 1/20 0.47
ALOX15 P16050 1/20 0.47
TSHR P16473 1/20 0.47
HSD17B10 Q99714 1/20 0.47
TDP1 Q9NUW8 1/20 0.47
DGKA P23743 1/20 0.47
GAA P10253 1/20 0.46
ENPP2 Q13822 4/20 0.44
TRPV1 Q8NER1 1/20 0.44
LPAR6 P43657 1/20 0.44
LPAR1 Q92633 1/20 0.44
LPAR4 Q99677 1/20 0.44
LPAR5 Q9H1C0 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25063817 1.00 LPAR3 (0.52) LPAR3LPAR2CYP1A2ALDH1A1CYP3A4
SCHEMBL25263033 1.00 LPAR3 (0.52) LPAR3LPAR2CYP1A2ALDH1A1CYP3A4
SCHEMBL11372070 0.96 CYP1A2 (0.52) LPAR3LPAR2CYP1A2ALDH1A1CYP3A4
SCHEMBL27789899 0.92 CYP1A2 (0.55) LPAR3LPAR2CYP1A2ALDH1A1CYP3A4
Diethylamine SCHEMBL27831406 0.84 CYP1A2 (0.47) LPAR3LPAR2CYP1A2GAA
SCHEMBL12227383 0.84 DGKA (0.56) LPAR3LPAR2TSHRDGKAENPP2
SCHEMBL1556696 0.84 SMN1; SMN2 (0.50) LPAR3LPAR2CYP1A2ALDH1A1ALOX15
SCHEMBL33870 0.83 CYP1A2 (0.70) CYP1A2ALDH1A1CYP3A4ALOX15TSHR
SCHEMBL495925 0.83 CYP1A2 (0.70) CYP1A2ALDH1A1CYP3A4ALOX15TSHR
SCHEMBL440349 0.83 CYP1A2 (0.70) CYP1A2ALDH1A1CYP3A4ALOX15TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 51 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12163188-B2 Polymerase compositions and methods Life Technologies Corporation (US) 2024-12-10 US disclosed
US-20230055565-A1 POLYMERASE COMPOSITIONS & METHODS Life Technologies Corporation (US) 2023-02-23 US disclosed
US-11453909-B2 Polymerase compositions and methods Life Technologies Corporation (US) 2022-09-27 US disclosed
US-11015220-B2 Conjugates of biomolecules to nanoparticles Life Technologies Corporation (US) 2021-05-25 US disclosed
US-11015220-B2 Conjugates of biomolecules to nanoparticles Life Technologies Corporation (US) 2021-05-25 US disclosed
US-11008612-B2 Methods and apparatus for single molecule sequencing using energy transfer detection Life Technologies Corporation (US) 2021-05-18 US disclosed
US-11008612-B2 Methods and apparatus for single molecule sequencing using energy transfer detection Life Technologies Corporation (US) 2021-05-18 US disclosed
US-10093974-B2 Methods and apparatus for single molecule sequencing using energy transfer detection Life Technologies Corporation (US) 2018-10-09 US disclosed
US-10093972-B2 Conjugates of biomolecules to nanoparticles Life Technologies Corporation (US) 2018-10-09 US disclosed
US-10093973-B2 Polymerase compositions and methods Life Technologies Corporation (US) 2018-10-09 US disclosed
US-20110014612-A1 POLYMERASE COMPOSITIONS & METHODS Life Technologies Corporation (US) 2011-01-20 US disclosed
US-20110014612-A1 POLYMERASE COMPOSITIONS & METHODS Life Technologies Corporation (US) 2011-01-20 US disclosed
WO-2010111691-A9 CONJUGATES OF BIOMOLECULES TO NANOPARTICLES LIFE TECHNOLOGIES CORP (US) 2011-01-06 WO disclosed
US-20110003343-A1 CONJUGATES OF BIOMOLECULES TO NANOPARTICLES Life Technologies Corporation (US) 2011-01-06 US disclosed
US-20110003343-A1 CONJUGATES OF BIOMOLECULES TO NANOPARTICLES Life Technologies Corporation (US) 2011-01-06 US disclosed
US-20100255487-A1 METHODS AND APPARATUS FOR SINGLE MOLECULE SEQUENCING USING ENERGY TRANSFER DETECTION Life Technologies Corporation (US) 2010-10-07 US disclosed
WO-2010111691-A2 CONJUGATES OF BIOMOLECULES TO NANOPARTICLES LIFE TECHNOLOGIES CORP (US) 2010-09-30 WO disclosed
WO-2010111690-A2 POLYMERASE COMPOSITIONS AND METHODS Life Technologies Corporation (US) 2010-09-30 WO disclosed
WO-2010111674-A2 METHODS AND APPARATUS FOR SINGLE MOLECULE SEQUENCING USING ENERGY TRANSFER DETECTION Life Technologies Corporation (US) 2010-09-30 WO disclosed
WO-2010039897-A2 NANOCRYSTALS WITH FUNCTIONAL LIGANDS Life Technologies Corporation (US) 2010-04-08 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (9 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11015220-B2 Conjugates of biomolecules to nanoparticles POLN, RNGTT, POLI LPAR3 944/4885LPAR2 1801/4885CYP1A2 3849/4885
US-20110014612-A1 POLYMERASE COMPOSITIONS & METHODS POLN, POLI, POLRMT LPAR3 2299/4885LPAR2 2968/4885CYP1A2 3403/4885
US-10093973-B2 Polymerase compositions and methods POLN, POLI, POLRMT LPAR3 2198/4885LPAR2 3001/4885CYP1A2 3681/4885
US-11453909-B2 Polymerase compositions and methods POLN, POLI, POLRMT LPAR3 2198/4885LPAR2 3001/4885CYP1A2 3681/4885
US-10093974-B2 Methods and apparatus for single molecule sequencing using energy transfer detection POLRMT, DNTT, POLM LPAR3 3839/4885LPAR2 4029/4885CYP1A2 4311/4885
US-11008612-B2 Methods and apparatus for single molecule sequencing using energy transfer detection POLRMT, DNTT, POLM LPAR3 3839/4885LPAR2 4029/4885CYP1A2 4311/4885
US-12163188-B2 Polymerase compositions and methods POLN, POLI, POLRMT LPAR3 2198/4885LPAR2 3001/4885CYP1A2 3681/4885
US-20230055565-A1 POLYMERASE COMPOSITIONS & METHODS POLN, POLI, POLRMT LPAR3 2299/4885LPAR2 2968/4885CYP1A2 3403/4885
US-10093972-B2 Conjugates of biomolecules to nanoparticles POLN, RNGTT, POLI LPAR3 944/4885LPAR2 1801/4885CYP1A2 3849/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.