SCHEMBL1060378

SCHEMBL1060378

CCCCC(=O)C(O)=S

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL724256 0.92 CES2 (0.67)
SCHEMBL31429807 0.90 CES2 (0.68)
SCHEMBL31429796 0.90 CES2 (0.68)
SCHEMBL6300373 0.90 CES2 (0.68)
SCHEMBL166461 0.83
SCHEMBL26674093 0.81
SCHEMBL2846729 0.80 CES1 (1.00)
SCHEMBL60653 0.78
SCHEMBL21114376 0.78 CES1 (0.72)
SCHEMBL154915 0.77

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12577201-B2 Glutamine analogs JACOBIO PHARMACEUTICALS CO., LTD. (CN) 2026-03-17 US claimed
EP-3887353-A1 PANTETHEINE DERIVATIVES AND USES THEREOF Comet Therapeutics, Inc. (US) 2021-10-06 EP disclosed
WO-2020113209-A1 PANTETHEINE DERIVATIVES AND USES THEREOF COMET THERAPEUTICS, INC. (US) 2020-06-04 WO disclosed
US-9096863-B2 Biosynthetic engineering of glucosinolates University of Denmark (DK) 2015-08-04 US disclosed
US-20110016582-A1 Biosynthetic Engineering of Glucosinolates UNIVERSITY OF COPENHAGEN (DK) 2011-01-20 US disclosed
US-6977297-B1 Methods and means for modification of glucosinolates in plants PLANT BIOSCIENCE LIMITED (GB) 2005-12-20 US disclosed
WO-2003012088-A2 NUCLEIC ACID MOLECULES ENCODING A GLUCOSINOLATE SULFATASE MAX-PLANCK-GESELLSCHAFT ZUR FÖRDERUNG DER WISSCNSCHAFTEN E.V. (DE) 2003-02-13 WO disclosed
EP-1032691-A1 METHODS AND MEANS FOR MODIFICATION OF GLUCOSINOLATES IN PLANTS Plant Bioscience Limited (GB) 2000-09-06 EP disclosed
WO-1999027120-A1 METHODS AND MEANS FOR MODIFICATION OF GLUCOSINOLATES IN PLANTS PLANT BIOSCIENCE LIMITED (GB) 1999-06-03 WO disclosed
EP-0206460-B1 L-PHENYLALANINE DEHYDROGENASE AND USE THEREOF SAGAMI CHEMICAL RESEARCH CENTER (JP) 1993-08-11 EP disclosed
EP-0513872-A1 L-phenylalanine dehydrogenase and use thereof SAGAMI CHEMICAL RESEARCH CENTER (JP) 1992-11-19 EP disclosed
US-4849345-A L-phenylalanine dehydrogenase and use thereof SAGAMI CHEMICAL RESEARCH CENTER (JP) 1989-07-18 US disclosed
EP-0206460-A2 L-phenylalanine dehydrogenase and use thereof SAGAMI CHEMICAL RESEARCH CENTER (JP) 1986-12-30 EP disclosed