Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 5/20 | 0.67 |
| ▸ | CES1 | P23141 | 5/20 | 0.67 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.56 |
| ▸ | GPR84 | Q9NQS5 | 7/20 | 0.54 |
| ▸ | PPARG | P37231 | 7/20 | 0.54 |
| ▸ | PPARD | Q03181 | 7/20 | 0.54 |
| ▸ | PPARA | Q07869 | 7/20 | 0.54 |
| ▸ | HDAC11 | Q96DB2 | 5/20 | 0.54 |
| ▸ | TSHR | P16473 | 4/20 | 0.54 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.54 |
| ▸ | TLR2 | O60603 | 2/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.54 |
| ▸ | FABP4 | P15090 | 2/20 | 0.54 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.54 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | ESR1 | P03372 | 1/20 | 0.54 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.54 |
| ▸ | PDE4A | P27815 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31429796 | 0.98 | CES2 (0.68) | CES2CES1AKR1B1GPR84PPARG | |
| SCHEMBL6300373 | 0.98 | CES2 (0.68) | CES2CES1AKR1B1GPR84PPARG | |
| SCHEMBL31429807 | 0.98 | CES2 (0.68) | CES2CES1AKR1B1GPR84PPARG | |
| SCHEMBL1060378 | 0.92 | — | — | |
| SCHEMBL166461 | 0.81 | — | — | |
| SCHEMBL3293052 | 0.81 | CES1 (1.00) | CES2CES1AKR1B1GPR84PPARG | |
| SCHEMBL128063 | 0.79 | CES2 (0.74) | CES2CES1AKR1B1GPR84PPARG | |
| SCHEMBL26674093 | 0.79 | — | — | |
| SCHEMBL6849632 | 0.78 | CES2 (1.00) | CES2CES1GPR84PPARGPPARD | |
| SCHEMBL11438920 | 0.78 | CES2 (1.00) | CES2CES1GPR84PPARGPPARD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2257630-B1 | BIOSYNTHETIC ENGINEERING OF GLUCOSINOLATES | UNIV COPENHAGEN (DK) | 2016-09-28 | — | — | EP | disclosed |
| US-9096863-B2 | Biosynthetic engineering of glucosinolates | University of Denmark (DK) | 2015-08-04 | — | — | US | disclosed |
| EP-2609077-A1 | PROCESS FOR PREPARING SULFUR-CONTAINING 2-KETOCARBOXYLATE COMPOUND | Sumitomo Chemical Company Limited (JP) | 2013-07-03 | — | — | EP | disclosed |
| EP-2609076-A1 | PROCESS FOR PREPARING SULFUR-CONTAINING 2-KETOCARBOXYLATE COMPOUND | Sumitomo Chemical Co., Ltd (JP) | 2013-07-03 | — | — | EP | disclosed |
| US-20130137896-A1 | PROCESS FOR PREPARING SULFUR-CONTAINING 2-KETOCARBOXYLATE COMPOUND | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2013-05-30 | — | — | US | disclosed |
| US-20130137897-A1 | PROCESS FOR PREPARING SULFUR-CONTAINING 2-KETOCARBOXYLATE COMPOUND | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2013-05-30 | — | — | US | disclosed |
| WO-2012026620-A1 | PROCESS FOR PREPARING SULFUR-CONTAINING 2-KETOCARBOXYLATE COMPOUND | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2012-03-01 | — | — | WO | disclosed |
| WO-2012026619-A1 | PROCESS FOR PREPARING SULFUR-CONTAINING 2-KETOCARBOXYLATE COMPOUND | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2012-03-01 | — | — | WO | disclosed |
| US-20110016582-A1 | Biosynthetic Engineering of Glucosinolates | UNIVERSITY OF COPENHAGEN (DK) | 2011-01-20 | — | — | US | disclosed |
| EP-2257630-A2 | BIOSYNTHETIC ENGINEERING OF GLUCOSINOLATES | University of Copenhagen (DK) | 2010-12-08 | — | — | EP | disclosed |
| WO-2009106985-A2 | BIOSYNTHETIC ENGINEERING OF GLUCOSINOLATES | UNIVERSITY OF COPENHAGEN (DK) | 2009-09-03 | — | — | WO | disclosed |
| US-6977297-B1 | Methods and means for modification of glucosinolates in plants | PLANT BIOSCIENCE LIMITED (GB) | 2005-12-20 | — | — | US | disclosed |
| EP-1032691-A1 | METHODS AND MEANS FOR MODIFICATION OF GLUCOSINOLATES IN PLANTS | Plant Bioscience Limited (GB) | 2000-09-06 | — | — | EP | disclosed |
| WO-1999027120-A1 | METHODS AND MEANS FOR MODIFICATION OF GLUCOSINOLATES IN PLANTS | PLANT BIOSCIENCE LIMITED (GB) | 1999-06-03 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130137896-A1 | PROCESS FOR PREPARING SULFUR-CONTAINING 2-KETOCARBOXYLATE COMPOUND | HPD, STS, HACL2 | CES2 883/4885CES1 371/4885AKR1B1 213/4885 |
| US-20130137897-A1 | PROCESS FOR PREPARING SULFUR-CONTAINING 2-KETOCARBOXYLATE COMPOUND | HPD, STS, HAO2 | CES2 748/4885CES1 529/4885AKR1B1 231/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.