SCHEMBL166461

SCHEMBL166461

CCCC(=O)C(O)=S

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26674093 0.97
SCHEMBL1060378 0.83
SCHEMBL724256 0.81 CES2 (0.67)
SCHEMBL31429796 0.79 CES2 (0.68)
SCHEMBL6300373 0.79 CES2 (0.68)
SCHEMBL31429807 0.79 CES2 (0.68)
SCHEMBL108642 0.77 CES1 (1.00)
SCHEMBL24359 0.75
SCHEMBL8769132 0.75 CES2 (0.69)
SCHEMBL17449772 0.75

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 384 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110869503-B Methionine producing yeast 安迪苏法国联合股份有限公司 2024-09-27 CN claimed
CN-118243934-A Use of serum markers for the preparation of products for diagnosis/prognosis of rheumatoid arthritis 海南医学院 2024-06-25 CN claimed
CN-110869488-B Enhanced metabolite producing yeast 安迪苏法国联合股份有限公司 2024-04-05 CN claimed
CN-110892073-B Enhanced metabolite producing yeast 安迪苏法国联合股份有限公司 2024-03-01 CN claimed
EP-3652319-B1 METHIONINE-PRODUCING YEAST ADISSEO FRANCE SAS (FR) 2023-10-25 EP claimed
EP-3652321-B9 ENHANCED METABOLITE-PRODUCING SACCHAROMYCES CEREVISIAE ADISSEO FRANCE SAS (FR) 2023-10-04 EP claimed
EP-3652321-B1 ENHANCED METABOLITE-PRODUCING SACCHAROMYCES CEREVISIAE ADISSEO FRANCE SAS (FR) 2023-06-07 EP claimed
US-11608488-B2 Enhanced metabolite-producing yeast ADISSEO FRANCE S.A.S. (FR) 2023-03-21 US claimed
US-20220204918-A1 CELL CULTURE MEDIA COMPRISING KETO ACIDS MERCK PATENT GMBH (DE) 2022-06-30 US claimed
US-20220193016-A1 COMPOSITIONS, METHODS AND USES FOR TARGETING C-TERMINAL BINDING PROTEIN (CtBP) IN TRAUMATIC BRAIN INJURY THE REGENTS OF THE UNIVERSITY OF COLORADO, A BODY CORPORATE 2022-06-23 US claimed
US-20130204016-A1 METHOD FOR PREPARING 2-HYDROXYBUTYROLACTONE ADISSEO FRANCE S.A.S. (FR) 2013-08-08 US claimed
CN-103068787-A Method for producing acrolein from glycerol or glycerin ADISSEO FRANCE SAS 2013-04-24 CN claimed
WO-2013050324-A1 COMBINATION, CONTAINING 4-PHENYLBUTYRIC ACID (4-PBA) OR A SALT THEREOF (COMPONENT (A)) AND ONE OR MORE SELECTED ADDITIONAL AGRONOMICALLY ACTIVE COMPOUNDS (COMPONENT(S) (B)), THAT REDUCES ABIOTIC PLANT STRESS BAYER INTELLECTUAL PROPERTY GMBH (DE) 2013-04-11 WO claimed
WO-2012091158-A1 A PROCESS FOR 2-OXO-4-METHYLTHIOBUTANOIC ACID OR SALTS THEREOF SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2012-07-05 WO claimed
WO-2012091159-A1 A PROCESS FOR 2-OXO-4-METHYLTHIOBUTANOIC ACID OR SALTS THEREOF SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2012-07-05 WO claimed
US-20120100255-A1 PRODUCTION OF NATURAL TRUFFLE FLAVOURS FROM TRUFFLE MYCELIUM SPLIVALLO RICHARD (CH) 2012-04-26 US claimed
EP-1831160-B1 SYNTHESIS AND USES OF 2-OXO-4-METHYLTHIOBUTYRIC ACID, ITS SALTS AND ITS DERIVATIVES ADISSEO IRELAND LTD (IE) 2010-06-30 EP claimed
US-7662997-B2 Synthesis and applications of 2-oxo-4-methylthiobutyric acid, its salts and its derivatives ADISSEO IRELAND LIMITED (IE) 2010-02-16 US claimed
US-20080069920-A1 Synthesis and Applications of 2-Oxo-4-Methylthiobutyric Acid, Its Salts and Its Derivatives ADISSEO IRELAND LIMITED (IE) 2008-03-20 US claimed
US-4100293-A Treatment of hepatic disorders with therapeutic compositions comprising keto analogs of essential amino acids THE JOHNS HOPKINS UNIVERSITY (US) 1978-07-11 US claimed