SCHEMBL10604256

SCHEMBL10604256

CC(C)Oc1ccc2cccc(OC(C)C)c2c1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MCHR1 Q99705 1/20 0.50
IRAK4 Q9NWZ3 2/20 0.45
MAPT P10636 2/20 0.45
CYP1A2 P05177 1/20 0.45
CYP2C9 P11712 1/20 0.45
CYP2C19 P33261 1/20 0.45
ITK Q08881 1/20 0.42
F2 P00734 2/20 0.42
PLG P00747 2/20 0.42
PLAU P00749 2/20 0.42
PLAT P00750 2/20 0.42
KLKB1 P03952 2/20 0.42
PRSS1 P07477 2/20 0.42
PPARG P37231 4/20 0.40
PPARA Q07869 4/20 0.40
ALDH1A1 P00352 2/20 0.40
TLR8 Q9NR97 1/20 0.39
MTNR1A P48039 3/20 0.39
NQO2 P16083 1/20 0.39
NPSR1 Q6W5P4 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15773008 0.90 NQO1 (0.47) MCHR1MAPTCYP1A2ITKF2
SCHEMBL7847800 0.90 NPSR1 (0.50) MCHR1MAPTCYP1A2CYP2C9CYP2C19
SCHEMBL15772429 0.86 MCHR1 (0.46) MCHR1IRAK4MAPTCYP1A2CYP2C9
SCHEMBL27760704 0.81 IRAK4 (0.47) MCHR1IRAK4MAPTCYP1A2CYP2C9
SCHEMBL9502674 0.81 CTDSP1 (0.49) IRAK4CYP1A2ITKF2PLG
SCHEMBL30600108 0.80 IRAK4 (0.46) MCHR1IRAK4MAPTCYP1A2CYP2C9
SCHEMBL4982131 0.79 CYP1A2 (0.56) MCHR1MAPTCYP1A2CYP2C9CYP2C19
SCHEMBL276584 0.77 CYP1A2 (0.58) IRAK4MAPTCYP1A2PPARGPPARA
SCHEMBL4600694 0.76 CYP2D6 (0.53) MCHR1IRAK4MAPTCYP1A2MTNR1A
SCHEMBL15772680 0.76 NQO1 (0.47) MCHR1IRAK4CYP1A2ALDH1A1NPSR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10364217-B2 Chemical compounds RESMAN AS (NO) 2019-07-30 US disclosed
US-9465288-B2 Sulfonium salt compound, method for producing the same, and photoacid generator DSP GOKYO FOOD & CHEMICAL CO., LTD. (JP) 2016-10-11 US disclosed
US-20160214930-A1 CHEMICAL COMPOUNDS RESMAN AS (NO) 2016-07-28 US disclosed
US-20150293445-A1 NOVEL SULFONIUM SALT COMPOUND, METHOD FOR PRODUCING THE SAME, AND PHOTOACID GENERATOR MP GOKYO FOOD & CHEMICAL CO., LTD. (JP) 2015-10-15 US disclosed
US-20150094240-A1 CHEMICAL COMPOUNDS RESMAN AS (NO) 2015-04-02 US disclosed
US-8952204-B2 Sulfonium salt, method for producing the same, and photoacid generator DSP GOKYO FOOD & CHEMICAL CO., LTD. (JP) 2015-02-10 US disclosed
US-20140163254-A1 NOVEL SULFONIUM SALT, METHOD FOR PRODUCING THE SAME, AND PHOTOACID GENERATOR MP GOKYO FOOD & CHEMICAL CO., LTD. (JP) 2014-06-12 US disclosed
EP-0189760-B1 THERMOSENSITIVE RECORDING SHEET JUJO PAPER CO., LTD. (JP) 1989-07-19 EP disclosed
US-4721701-A Thermosensitive recording sheet JUJO PAPER CO., LTD. (JP) 1988-01-26 US disclosed
EP-0189760-A1 Thermosensitive recording sheet JUJO PAPER CO., LTD. (JP) 1986-08-06 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160214930-A1 CHEMICAL COMPOUNDS PTGES, PTGIS, PTGFR MCHR1 1287/4885IRAK4 4255/4885MAPT 734/4885
US-20150094240-A1 CHEMICAL COMPOUNDS PTGES, PTGIS, PTGFR MCHR1 1287/4885IRAK4 4255/4885MAPT 734/4885
US-20150293445-A1 NOVEL SULFONIUM SALT COMPOUND, METHOD FOR PRODUCING THE SAME, AND PHOTOACID GENERATOR FGFR1, ARSA, PAOX MCHR1 2956/4885IRAK4 2106/4885MAPT 3406/4885
US-10364217-B2 Chemical compounds PTGES, PTGIS, PTGFR MCHR1 1287/4885IRAK4 4255/4885MAPT 734/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.