Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | ITK | Q08881 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | PNLIP | P16233 | 1/20 | 0.41 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.41 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.41 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.41 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.41 |
| ▸ | MTNR1A | P48039 | 3/20 | 0.41 |
| ▸ | PLG | P00747 | 2/20 | 0.41 |
| ▸ | PLAU | P00749 | 2/20 | 0.41 |
| ▸ | PLAT | P00750 | 2/20 | 0.41 |
| ▸ | NQO2 | P16083 | 1/20 | 0.41 |
| ▸ | F2 | P00734 | 1/20 | 0.41 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.41 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26725170 | 0.86 | PLAU (0.49) | CYP1A2ALDH1A1PNLIPGRIN2DGRIN2A | |
| SCHEMBL7079680 | 0.82 | MTNR1A (0.48) | CTDSP1GRIN2DGRIN2AGRIN2BGRIN2C | |
| SCHEMBL27504643 | 0.81 | CYP3A4 (0.54) | CTDSP1GRIN2DGRIN2AGRIN2BGRIN2C | |
| SCHEMBL10604256 | 0.81 | MCHR1 (0.50) | CYP1A2ITKALDH1A1MTNR1APLG | |
| SCHEMBL169434 | 0.80 | MTNR1A (0.55) | CTDSP1CYP1A2MTNR1ANQO2MTNR1B | |
| SCHEMBL16187157 | 0.79 | CTDSP1 (0.45) | CTDSP1CYP1A2GRIN2DGRIN2AGRIN2B | |
| SCHEMBL15773008 | 0.78 | NQO1 (0.47) | CYP1A2ITKALDH1A1MTNR1APLG | |
| SCHEMBL9610674 | 0.76 | ELANE (0.47) | CTDSP1CYP1A2GRIN2DGRIN2AGRIN2B | |
| SCHEMBL276584 | 0.75 | CYP1A2 (0.58) | CYP1A2ALDH1A1KMT2AIRAK4PPARG | |
| SCHEMBL18674135 | 0.75 | CYP1A2 (0.52) | CTDSP1CYP1A2ALDH1A1GRIN2DGRIN2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0279466-B1 | NOVEL NAPHTHALENE DERIVATIVES AND ANTIALLERGY AND ANTI-INFLAMMATORY PHARMACEUTICALS | WARNER-LAMBERT COMPANY (US) | 1993-05-19 | — | — | EP | disclosed |
| US-4767776-A | N-1H-tetrazol-5-yl-2-naphthalene carboxamides and their use as antiallergy and antiinflammatory agents | WARNER-LAMBERT COMPANY (US) | 1988-08-30 | — | — | US | disclosed |
| EP-0279466-A2 | Novel naphthalene derivatives and antiallergy and anti-inflammatory pharmaceuticals | WARNER-LAMBERT COMPANY (US) | 1988-08-24 | — | — | EP | disclosed |