Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA3 | P0DMS8 | 3/20 | 0.57 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.57 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.57 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | HPGDS | O60760 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | MAOA | P21397 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.38 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.38 |
| ▸ | RELA | Q04206 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1292908 | 0.78 | ADORA3 (0.53) | ADORA3ADORA2AADORA1ALDH1A1HPGDS | |
| SCHEMBL2885131 | 0.76 | HPGDS (0.41) | ADORA3ADORA2AADORA1LMNAHPGD | |
| SCHEMBL9119522 | 0.76 | CDK5 (0.46) | ADORA3ADORA2AADORA1ADORA2BLMNA | |
| SCHEMBL889310 | 0.74 | HSD17B10 (0.39) | ADORA3ADORA2AADORA1ADORA2BKDM4E | |
| SCHEMBL890084 | 0.74 | HSD17B10 (0.39) | ADORA3ADORA2AADORA1ADORA2BKDM4E | |
| SCHEMBL29448112 | 0.71 | MEN1 (0.45) | ADORA3LMNAALDH1A1HPGDHPGDS | |
| SCHEMBL22777765 | 0.71 | MEN1 (0.45) | ADORA3LMNAALDH1A1HPGDHPGDS | |
| SCHEMBL888691 | 0.70 | HSD17B10 (0.36) | ADORA3ADORA2AADORA1ADORA2BKDM4E | |
| SCHEMBL12810051 | 0.70 | HSD17B10 (0.36) | ADORA3ADORA2AADORA1ADORA2BKDM4E | |
| SCHEMBL680856 | 0.69 | CDK2 (0.55) | ADORA3ADORA2AADORA1KDM4EHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0181129-B1 | N6-SUBSTITUTED DEOXYRIBOSE ANALOGS OF ADENOSINES | WARNER-LAMBERT COMPANY (US) | 1989-03-08 | — | — | EP | disclosed |
| EP-0181129-A2 | N6-substituted deoxyribose analogs of adenosines | WARNER-LAMBERT COMPANY (US) | 1986-05-14 | — | — | EP | disclosed |