Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGDS | O60760 | 4/20 | 0.41 |
| ▸ | NPC1 | O15118 | 3/20 | 0.41 |
| ▸ | RAB9A | P51151 | 3/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.41 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.41 |
| ▸ | RELA | Q04206 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | ADORA3 | P0DMS8 | 4/20 | 0.39 |
| ▸ | ADORA2A | P29274 | 3/20 | 0.38 |
| ▸ | ADORA1 | P30542 | 3/20 | 0.38 |
| ▸ | NR1H2 | P55055 | 2/20 | 0.38 |
| ▸ | NR1H3 | Q13133 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | HTR2C | P28335 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | ALPL | P05186 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1292908 | 0.81 | ADORA3 (0.53) | HPGDSNPC1RAB9ASMN1; SMN2NFKB1 | |
| SCHEMBL9119522 | 0.80 | CDK5 (0.46) | HPGDSNPC1RAB9ASMN1; SMN2NFKB1 | |
| SCHEMBL10604271 | 0.76 | ADORA3 (0.57) | HPGDSNPC1RAB9ASMN1; SMN2NFKB1 | |
| SCHEMBL22777765 | 0.74 | MEN1 (0.45) | HPGDSNPC1RAB9ASMN1; SMN2NFKB1 | |
| SCHEMBL29448112 | 0.74 | MEN1 (0.45) | HPGDSNPC1RAB9ASMN1; SMN2NFKB1 | |
| SCHEMBL31665906 | 0.73 | NOS3 (0.49) | NPC1CYP3A4 | |
| SCHEMBL2885130 | 0.73 | NPC1 (0.42) | HPGDSNPC1RAB9ASMN1; SMN2NFKB1 | |
| SCHEMBL680856 | 0.72 | CDK2 (0.55) | HPGDSNPC1RAB9ASMN1; SMN2NFKB1 | |
| SCHEMBL539008 | 0.72 | KDM4E (0.53) | NPC1RAB9A | |
| Hydrochloric Acid SCHEMBL4456682 | 0.71 | CDK2 (0.54) | HPGDSNPC1RAB9ASMN1; SMN2NFKB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7691860-B2 | Sulfonamide derivatives | BANYU PHARMACEUTICAL CO., LTD. (JP) | 2010-04-06 | — | — | US | disclosed |
| CN-100567270-C | Sulfone amide derivative | BANYU PHARMA CO LTD (JP) | 2009-12-09 | — | — | CN | disclosed |
| US-20080161326-A1 | Novel Sulfone Amide Amide Derivatives | MSD K.K. (JP) | 2008-07-03 | — | — | US | disclosed |
| CN-1922155-A | Novel Sulfonamide Derivatives | BANYU PHARMA CO LTD (JP) | 2007-02-28 | — | — | CN | disclosed |
| EP-1719765-A1 | NOVEL SULFONE AMIDE DERIVATIVE | BANYU PHARMACEUTICAL CO., LTD. (JP) | 2006-11-08 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080161326-A1 | Novel Sulfone Amide Amide Derivatives | NPY1R, NPY2R, NPY5R | HPGDS 1159/4885NPC1 3164/4885RAB9A 2356/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.