Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | GAA | P10253 | 4/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | USP2 | O75604 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10604575 | 0.77 | KMT2A (0.36) | KMT2AGAAALDH1A1KDM4EHPGD | |
| SCHEMBL21368249 | 0.71 | KDM4E (0.55) | KMT2AGAAALDH1A1KDM4EHPGD | |
| SCHEMBL10606300 | 0.70 | GAA (0.45) | KMT2AGAAALDH1A1KDM4EHPGD | |
| SCHEMBL8972507 | 0.65 | KMT2A (0.41) | KMT2AGAAALDH1A1KDM4EHPGD | |
| SCHEMBL23870613 | 0.64 | KMT2A (0.39) | KMT2AGAAALDH1A1KDM4EHPGD | |
| SCHEMBL6934957 | 0.64 | KMT2A (0.39) | KMT2AGAAALDH1A1KDM4EHPGD | |
| SCHEMBL29091543 | 0.63 | GAA (0.58) | KMT2AGAAALDH1A1KDM4EHPGD | |
| SCHEMBL10604566 | 0.63 | MEN1 (0.41) | KMT2AGAAALDH1A1KDM4EHPGD | |
| SCHEMBL8973254 | 0.62 | KMT2A (0.38) | KMT2AGAAALDH1A1KDM4EHPGD | |
| SCHEMBL8756210 | 0.62 | KMT2A (0.43) | KMT2AGAAALDH1A1KDM4EHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0107492-B1 | HELICHROMIC-SMECTIC LIQUID CRYSTAL COMPOSITIONS AND DISPLAY CELLS | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1989-08-09 | — | — | EP | claimed |
| US-4514045-A | DICHROISM; COMPLETE LIGHT ABSORPTION; LOW VOLTAGE; CONTRAST | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1985-04-30 | — | — | US | claimed |
| EP-0107492-A2 | Helichromic-smectic liquid crystal compositions and display cells | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1984-05-02 | — | — | EP | claimed |