Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 10/20 | 0.55 |
| ▸ | MAPT | P10636 | 10/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.55 |
| ▸ | GAA | P10253 | 7/20 | 0.55 |
| ▸ | HPGD | P15428 | 6/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 8/20 | 0.50 |
| ▸ | MEN1 | O00255 | 7/20 | 0.40 |
| ▸ | NSD2 | O96028 | 4/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.40 |
| ▸ | APP | P05067 | 2/20 | 0.40 |
| ▸ | SNCA | P37840 | 2/20 | 0.40 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.40 |
| ▸ | RAD52 | P43351 | 1/20 | 0.37 |
| ▸ | APAF1 | O14727 | 2/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | BRPF1 | P55201 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.35 |
| ▸ | CASP1 | P29466 | 1/20 | 0.35 |
| ▸ | CASP7 | P55210 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30738818 | 0.78 | BRPF1 (0.50) | KDM4EMAPTALDH1A1GAAHPGD | |
| SCHEMBL4013751 | 0.78 | BRPF1 (0.50) | KDM4EMAPTALDH1A1GAAHPGD | |
| SCHEMBL8972507 | 0.75 | KMT2A (0.41) | KDM4EMAPTALDH1A1GAAHPGD | |
| SCHEMBL23870613 | 0.74 | KMT2A (0.39) | KDM4EMAPTALDH1A1GAAHPGD | |
| SCHEMBL6934957 | 0.74 | KMT2A (0.39) | KDM4EMAPTALDH1A1GAAHPGD | |
| SCHEMBL8973254 | 0.72 | KMT2A (0.38) | KDM4EMAPTALDH1A1GAAHPGD | |
| SCHEMBL8756210 | 0.71 | KMT2A (0.43) | KDM4EMAPTALDH1A1GAAHPGD | |
| SCHEMBL9161190 | 0.71 | ALDH1A1 (1.00) | KDM4EMAPTALDH1A1GAAHPGD | |
| SCHEMBL28489824 | 0.71 | KMT2A (0.55) | KDM4EMAPTALDH1A1GAAHPGD | |
| SCHEMBL10604558 | 0.71 | KMT2A (0.37) | KDM4EMAPTALDH1A1GAAHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019177689-A1 | CURABLE POLYSILOXANE COMPOSITION | DOW SILICONES CORPORATION (US) | 2019-09-19 | — | — | WO | disclosed |