Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 10/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.45 |
| ▸ | HPGD | P15428 | 6/20 | 0.45 |
| ▸ | ALOX12 | P18054 | 3/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 17/20 | 0.43 |
| ▸ | MAPT | P10636 | 7/20 | 0.39 |
| ▸ | MEN1 | O00255 | 16/20 | 0.37 |
| ▸ | THRB | P10828 | 3/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 6/20 | 0.36 |
| ▸ | HPN | P05981 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.34 |
| ▸ | NSD2 | O96028 | 1/20 | 0.34 |
| ▸ | APP | P05067 | 1/20 | 0.34 |
| ▸ | SNCA | P37840 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8317948 | 0.76 | GAA (0.56) | GAAALDH1A1KDM4EHPGDALOX12 | |
| SCHEMBL16504030 | 0.74 | GAA (0.50) | GAAALDH1A1KDM4EHPGDALOX12 | |
| SCHEMBL21368249 | 0.70 | KDM4E (0.55) | GAAALDH1A1KDM4EHPGDALOX12 | |
| SCHEMBL10604558 | 0.70 | KMT2A (0.37) | GAAALDH1A1KDM4EHPGDALOX12 | |
| SCHEMBL24074587 | 0.66 | KDM4E (0.75) | GAAALDH1A1KDM4EHPGDALOX12 | |
| SCHEMBL13012832 | 0.66 | KMT2A (0.44) | GAAALDH1A1KDM4EHPGDALOX12 | |
| SCHEMBL28489824 | 0.64 | KMT2A (0.55) | GAAALDH1A1KDM4EHPGDALOX12 | |
| Pyrene SCHEMBL16192632 | 0.64 | ALDH1A1 (0.58) | GAAALDH1A1KDM4EHPGDKMT2A | |
| SCHEMBL10604575 | 0.63 | KMT2A (0.36) | GAAALDH1A1KDM4EHPGDALOX12 | |
| SCHEMBL8318923 | 0.62 | KMT2A (0.41) | GAAALDH1A1KDM4EHPGDALOX12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0107492-B1 | HELICHROMIC-SMECTIC LIQUID CRYSTAL COMPOSITIONS AND DISPLAY CELLS | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1989-08-09 | — | — | EP | disclosed |
| US-4514045-A | DICHROISM; COMPLETE LIGHT ABSORPTION; LOW VOLTAGE; CONTRAST | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1985-04-30 | — | — | US | disclosed |
| EP-0107492-A2 | Helichromic-smectic liquid crystal compositions and display cells | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1984-05-02 | — | — | EP | disclosed |