Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.34 |
| ▸ | MAPT | P10636 | 5/20 | 0.34 |
| ▸ | GAA | P10253 | 4/20 | 0.34 |
| ▸ | HPGD | P15428 | 4/20 | 0.34 |
| ▸ | MEN1 | O00255 | 4/20 | 0.33 |
| ▸ | APAF1 | O14727 | 2/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.32 |
| ▸ | NR4A1 | P22736 | 2/20 | 0.31 |
| ▸ | APP | P05067 | 2/20 | 0.31 |
| ▸ | SNCA | P37840 | 2/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.31 |
| ▸ | USP2 | O75604 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | RAD52 | P43351 | 1/20 | 0.31 |
| ▸ | NSD2 | O96028 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8756210 | 0.81 | KMT2A (0.43) | KMT2AKDM4EALDH1A1MAPTGAA | |
| SCHEMBL8973254 | 0.80 | KMT2A (0.38) | KMT2AKDM4EALDH1A1MAPTGAA | |
| SCHEMBL21368249 | 0.74 | KDM4E (0.55) | KMT2AKDM4EALDH1A1MAPTGAA | |
| SCHEMBL8972507 | 0.71 | KMT2A (0.41) | KMT2AKDM4EALDH1A1MAPTGAA | |
| SCHEMBL23870613 | 0.70 | KMT2A (0.39) | KMT2AKDM4EALDH1A1MAPTGAA | |
| SCHEMBL6450576 | 0.65 | BRPF1 (0.44) | KMT2AKDM4EALDH1A1MAPTGAA | |
| SCHEMBL6934661 | 0.65 | KMT2A (0.37) | KMT2AKDM4EALDH1A1MAPTGAA | |
| SCHEMBL8824407 | 0.65 | ALDH1A1 (0.52) | KMT2AKDM4EALDH1A1MAPTGAA | |
| SCHEMBL10604558 | 0.64 | KMT2A (0.37) | KMT2AKDM4EALDH1A1MAPTGAA | |
| SCHEMBL339574 | 0.63 | MEN1 (0.52) | KMT2AKDM4EALDH1A1MAPTGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-RE38251-E1 | Dihydroperimidines | IMATION CORP. | 2003-09-16 | — | — | US | disclosed |