Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MC4R | P32245 | 2/20 | 0.47 |
| ▸ | MC3R | P41968 | 2/20 | 0.47 |
| ▸ | MC1R | Q01726 | 2/20 | 0.47 |
| ▸ | BCHE | P06276 | 2/20 | 0.44 |
| ▸ | SIGMAR1 | Q99720 | 4/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | FKBP1A | P62942 | 3/20 | 0.42 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.41 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.41 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.41 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.41 |
| ▸ | TMEM97 | Q5BJF2 | 3/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | HTR1A | P08908 | 1/20 | 0.41 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.41 |
| ▸ | HRH2 | P25021 | 1/20 | 0.41 |
| ▸ | HRH1 | P35367 | 1/20 | 0.41 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10604863 | 1.00 | MC4R (0.47) | MC4RMC3RMC1RBCHESIGMAR1 | |
| SCHEMBL10587876 | 1.00 | MC4R (0.47) | MC4RMC3RMC1RBCHESIGMAR1 | |
| Hydrochloric Acid SCHEMBL11012588 | 0.99 | MC4R (0.46) | MC4RMC3RMC1RBCHESIGMAR1 | |
| Hydrochloric Acid SCHEMBL11012994 | 0.99 | MC4R (0.46) | MC4RMC3RMC1RBCHESIGMAR1 | |
| SCHEMBL10798191 | 0.81 | FKBP1A (0.49) | MC4RMC3RMC1RSIGMAR1SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL30844756 | 0.80 | FKBP1A (0.48) | MC4RMC3RMC1RSIGMAR1SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL5474137 | 0.80 | FKBP1A (0.48) | MC4RMC3RMC1RSIGMAR1SMN1; SMN2 | |
| SCHEMBL924014 | 0.76 | GABRA1 (0.53) | SIGMAR1SMN1; SMN2NPC1RAB9AFKBP1A | |
| SCHEMBL2900931 | 0.76 | ALDH1A1 (0.50) | SMN1; SMN2NPC1RAB9ACYP2C19ALDH1A1 | |
| SCHEMBL13402324 | 0.74 | SCN1A (0.57) | SMN1; SMN2NPC1RAB9ACHRM2CHRM5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0146080-B1 | PROCESS FOR THE RACEMIC SEPARATION OF BICYCLIC ALPHA-IMINO CARBOXYLIC-ACID ESTERS | HOECHST AKTIENGESELLSCHAFT (DE) | 1989-07-26 | — | — | EP | disclosed |
| EP-0146080-A2 | Process for the racemic separation of bicyclic alpha-imino carboxylic-acid esters | HOECHST AKTIENGESELLSCHAFT (DE) | 1985-06-26 | — | — | EP | disclosed |