SCHEMBL10606

SCHEMBL10606

CC(C)(C)OC(=O)CCI

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HDAC6 Q9UBN7 3/20 0.37
HDAC1 Q13547 2/20 0.37
HDAC2 Q92769 2/20 0.37
HDAC3 O15379 1/20 0.37
HDAC8 Q9BY41 1/20 0.37
STING1 Q86WV6 1/20 0.35
DGAT1 O75907 1/20 0.34
CYP2D6 P10635 1/20 0.34
EPHX2 P34913 1/20 0.34
MTNR1A P48039 1/20 0.33
MTNR1B P49286 1/20 0.33
CA2 P00918 2/20 0.32
CA12 O43570 1/20 0.32
CA14 Q9ULX7 1/20 0.32
TSHR P16473 1/20 0.32
KDM4E B2RXH2 1/20 0.32
ALDH1A1 P00352 1/20 0.32
TDP1 Q9NUW8 1/20 0.31
CTSK P43235 2/20 0.31
MLYCD O95822 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL418887 0.86 EPHX2 (0.39) HDAC6HDAC1HDAC2HDAC3HDAC8
SCHEMBL21811526 0.84 EPHX2 (0.41) HDAC6HDAC1HDAC2HDAC3HDAC8
SCHEMBL644646 0.84 TSHR (0.45) HDAC6HDAC1HDAC2HDAC3HDAC8
SCHEMBL713362 0.82 EPHX2 (0.43) HDAC6HDAC1HDAC2HDAC3HDAC8
SCHEMBL10557596 0.82 EPHX2 (0.43) HDAC6HDAC1HDAC2HDAC3HDAC8
SCHEMBL9862468 0.82 EPHX2 (0.43) HDAC6HDAC1HDAC2HDAC3HDAC8
SCHEMBL3992478 0.82 EPHX2 (0.43) HDAC6HDAC1HDAC2HDAC3HDAC8
SCHEMBL2963000 0.82 HDAC6 (0.42) HDAC6HDAC1HDAC2HDAC3HDAC8
SCHEMBL21634210 0.81 STING1 (0.34) HDAC6HDAC1HDAC2HDAC3HDAC8
SCHEMBL17860728 0.79 ALDH1A1 (0.33) TSHRALDH1A1TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119013287-A Macrocyclic immunomodulators 百时美施贵宝公司 2024-11-22 CN disclosed
CN-118613490-A Macrocyclic immunomodulators 百时美施贵宝公司 2024-09-06 CN disclosed
CN-118076623-A Macrocyclic immunomodulators 百时美施贵宝公司 2024-05-24 CN disclosed
CN-117940445-A Macrocyclic immunomodulators 百时美施贵宝公司 2024-04-26 CN disclosed
US-11958802-B2 Migration-resistant photopolymerization sensitizer KAWASAKI KASEI CHEMICALS LTD. (JP) 2024-04-16 US disclosed
CN-114891070-A Anthelmintic depsipeptide compounds 勃林格殷格翰动物保健美国公司 2022-08-12 CN disclosed
CN-107835818-B Anthelmintic depsipeptide compounds 勃林格殷格翰动物保健美国公司 2022-04-29 CN disclosed
US-20220106254-A1 MIGRATION-RESISTANT PHOTOPOLYMERIZATION SENSITIZER KAWASAKI KASEI CHEMICALS LTD. (JP) 2022-04-07 US disclosed
CN-113166036-A Photopolymerisable sensitizers having migration resistance 川崎化成工业株式会社 2021-07-23 CN disclosed
WO-2020213442-A1 PHOTOPOLYMERIZABLE COMPOSITION, COATING FILM CONTAINING SAID PHOTOPOLYMERIZABLE COMPOSITION, AND CURING METHOD THEREFOR 川崎化成工業株式会社 2020-10-22 WO disclosed
US-20130046087-A1 Substituted Cyclodextrin Derivatives Useful As Intermediates For Producing Biologically Active Materials ARCARIOS BV (NL) 2013-02-21 US disclosed
US-8343975-B2 4-amino-3-(imidazolyl)-pyrazolo[3,4-D]pyrimidines CHEMOCENTRYX, INC. 2013-01-01 US disclosed
CN-102834416-A Substituted cyclodextrin derivatives useful as intermediates for producing biologically active materials ARCARIOS BV 2012-12-19 CN disclosed
WO-2011048936-A1 AMINOTHIAZOLE DERIVATIVE 大正製薬株式会社 (JP) 2011-04-28 WO disclosed
US-20090133473-A1 MAGNETIC GAS SENSOR AND METHODS USING ANTIFERROMAGNETIC HEMATITE NANOPARTICLES BOISE STATE UNIVERSITY (US) 2009-05-28 US disclosed
US-6018047-A GROUP Z-A-AT POSITION 10, WHERE A IS A DIVALENT ORGANIC MOIETY AND Z IS CAPABLE OF COUPLING A BIOACTIVE COMPOUND, AND AT POSITION 9 AN ESTER WHICH FORMS DIOXETANE WITH HYDROGEN PEROXIDE; USE IN HETEROGENEOUS AND HOMOGENEOUS IMMUNOASSAYS ZOMER GIJSBERT (NL) 2000-01-25 US disclosed
US-5521103-A Acridinium compounds as chemiluminogenic label MOCHIDA PHARMACEUTICAL CO., LTD. (JP) 1996-05-28 US disclosed
US-5512486-A Single step signal group-imidazole labeling of organic phosphate groups under aqueous conditions NORTHEASTERN UNIVERSITY (US) 1996-04-30 US disclosed
EP-0324202-B1 Acridinium compounds as chemiluminogenic label MOCHIDA PHARM CO LTD (JP) 1994-08-24 EP disclosed
EP-0324202-A1 Acridinium compounds as chemiluminogenic label MOCHIDA PHARMACEUTICAL CO., LTD. (JP) 1989-07-19 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11958802-B2 Migration-resistant photopolymerization sensitizer F12, F10, PCNA HDAC6 1799/4885HDAC1 1480/4885HDAC2 2254/4885
US-20220106254-A1 MIGRATION-RESISTANT PHOTOPOLYMERIZATION SENSITIZER F12, F10, PCNA HDAC6 1799/4885HDAC1 1480/4885HDAC2 2254/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.