Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL142215 | 0.86 | TSHR (0.39) | ALDH1A1TSHRTDP1 | |
| SCHEMBL8011953 | 0.84 | ALDH1A1 (0.35) | ALDH1A1TSHRTDP1 | |
| SCHEMBL17860695 | 0.83 | ALDH1A1 (0.33) | ALDH1A1 | |
| SCHEMBL1998916 | 0.82 | ALDH1A1 (0.50) | ALDH1A1TSHRTDP1 | |
| SCHEMBL12083658 | 0.80 | ALDH1A1 (0.35) | ALDH1A1TSHRTDP1 | |
| SCHEMBL10606 | 0.79 | HDAC6 (0.37) | ALDH1A1TSHRTDP1 | |
| SCHEMBL5524337 | 0.79 | ALDH1A1 (0.38) | ALDH1A1TSHRTDP1 | |
| SCHEMBL13785296 | 0.78 | EGLN1 (0.43) | ALDH1A1TSHRTDP1 | |
| SCHEMBL5069214 | 0.78 | ALDH1A1 (0.33) | ALDH1A1TSHRTDP1 | |
| SCHEMBL18513409 | 0.78 | TSHR (0.39) | ALDH1A1TSHRTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016100578-A2 | ANTIMICROBIAL POLYMYXINS FOR TREATMENT OF BACTERIAL INFECTIONS | MICURX PHARMACEUTICALS, INC. (US) | 2016-06-23 | — | — | WO | disclosed |