Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 13/20 | 0.68 |
| ▸ | ALDH1A1 | P00352 | 12/20 | 0.68 |
| ▸ | HPGD | P15428 | 8/20 | 0.68 |
| ▸ | MAPT | P10636 | 7/20 | 0.64 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.64 |
| ▸ | HTT | P42858 | 6/20 | 0.64 |
| ▸ | RAB9A | P51151 | 4/20 | 0.64 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.64 |
| ▸ | NPC1 | O15118 | 3/20 | 0.64 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.64 |
| ▸ | MEN1 | O00255 | 2/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.64 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.64 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.64 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.64 |
| ▸ | GFER | P55789 | 1/20 | 0.64 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.55 |
| ▸ | TSHR | P16473 | 3/20 | 0.55 |
| ▸ | TP53 | P04637 | 3/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10609312 | 0.83 | ALDH1A1 (0.74) | KDM4EALDH1A1HPGDMAPTSMN1; SMN2 | |
| SCHEMBL19275978 | 0.83 | KDM4E (0.77) | KDM4EALDH1A1HPGDMAPTSMN1; SMN2 | |
| SCHEMBL5009162 | 0.83 | KDM4E (0.77) | KDM4EALDH1A1HPGDMAPTSMN1; SMN2 | |
| SCHEMBL29991849 | 0.81 | KDM4E (0.73) | KDM4EALDH1A1HPGDMAPTSMN1; SMN2 | |
| SCHEMBL21777019 | 0.81 | KDM4E (1.00) | KDM4EALDH1A1HPGDMAPTSMN1; SMN2 | |
| SCHEMBL18969121 | 0.81 | KDM4E (0.73) | KDM4EALDH1A1HPGDMAPTSMN1; SMN2 | |
| SCHEMBL11313561 | 0.81 | KDM4E (0.73) | KDM4EALDH1A1HPGDMAPTSMN1; SMN2 | |
| SCHEMBL21769699 | 0.81 | KDM4E (0.73) | KDM4EALDH1A1HPGDMAPTSMN1; SMN2 | |
| SCHEMBL10608396 | 0.81 | KDM4E (0.65) | KDM4EALDH1A1HPGDMAPTSMN1; SMN2 | |
| SCHEMBL16692218 | 0.81 | KDM4E (0.73) | KDM4EALDH1A1HPGDMAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0126231-B1 | VINYLPHENYL BENZIMIDAZOLE DERIVATIVES, THEIR POLYMERS, THEIR PREPARATION AND USE | Asahi Kasei Kogyo Kabushiki Kaisha (JP) | 1989-12-20 | — | — | EP | disclosed |
| US-4533678-A | BENZIMIDAZOLYLSTYRENE POLYMERS | ASAHI KASEI KOGYO KABUSHIKI KAISHA (JP) | 1985-08-06 | — | — | US | disclosed |
| EP-0126231-A2 | Vinylphenyl benzimidazole derivatives, their polymers, their preparation and use | Asahi Kasei Kogyo Kabushiki Kaisha (JP) | 1984-11-28 | — | — | EP | disclosed |