SCHEMBL10608396

SCHEMBL10608396

C=Cc1ccc(-c2nc3ccccc3n2C)cc1

nearest known ligand 0.65

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 12/20 0.65
ALDH1A1 P00352 11/20 0.65
RAB9A P51151 6/20 0.65
TP53 P04637 5/20 0.65
HSD17B10 Q99714 5/20 0.65
PKM P14618 4/20 0.65
NPC1 O15118 4/20 0.65
GAA P10253 3/20 0.65
ALOX15 P16050 2/20 0.65
MEN1 O00255 4/20 0.62
KMT2A Q03164 4/20 0.62
HPGD P15428 7/20 0.61
MAPT P10636 6/20 0.61
SMN1; SMN2 Q16637 6/20 0.61
LMNA P02545 2/20 0.61
HTT P42858 2/20 0.61
GFER P55789 1/20 0.61
CA1 P00915 1/20 0.57
CA2 P00918 1/20 0.57
RXFP1 Q9HBX9 1/20 0.57

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14690274 0.87 ALDH1A1 (0.69) KDM4EALDH1A1RAB9ATP53HSD17B10
SCHEMBL14690273 0.87 ALDH1A1 (0.69) KDM4EALDH1A1RAB9ATP53HSD17B10
SCHEMBL20982597 0.87 ALDH1A1 (0.83) KDM4EALDH1A1RAB9ATP53HSD17B10
SCHEMBL28202091 0.85 RAB9A (0.50) KDM4EALDH1A1RAB9ATP53HSD17B10
SCHEMBL28569089 0.84 ALDH1A1 (0.65) KDM4EALDH1A1RAB9ATP53HSD17B10
SCHEMBL2242681 0.82 ALDH1A1 (0.75) KDM4EALDH1A1RAB9ATP53HSD17B10
SCHEMBL9611665 0.82 ALDH1A1 (0.75) KDM4EALDH1A1RAB9ATP53HSD17B10
Hydrochloric Acid SCHEMBL10611368 0.81 MEN1 (0.51) KDM4EALDH1A1RAB9ATP53HSD17B10
SCHEMBL517706 0.81 MEN1 (0.77) KDM4EALDH1A1RAB9ATP53HSD17B10
SCHEMBL10606552 0.81 KDM4E (0.68) KDM4EALDH1A1RAB9ATP53HSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-120424014-A Benzimidazole quaternary ammonium salt and preparation method and application thereof 南京神奇科技开发有限公司 2025-08-05 CN disclosed
US-9000111-B2 Thermoplastic resin, organic-inorganic hybrid composition and optical parts FUJIFILM CORPORATION (JP) 2015-04-07 US disclosed
US-9000111-B2 Thermoplastic resin, organic-inorganic hybrid composition and optical parts FUJIFILM CORPORATION (JP) 2015-04-07 US disclosed
US-20110135903-A1 THERMOPLASTIC RESIN, ORGANIC-INORGANIC HYBRID COMPOSITION AND OPTICAL PARTS FUJIFILM CORPORATION (JP) 2011-06-09 US disclosed
US-20110135903-A1 THERMOPLASTIC RESIN, ORGANIC-INORGANIC HYBRID COMPOSITION AND OPTICAL PARTS FUJIFILM CORPORATION (JP) 2011-06-09 US disclosed
WO-2010024463-A1 THERMOPLASTIC RESIN, ORGANIC-INORGANIC HYBRID COMPOSITION AND OPTICAL PARTS FUJIFILM CORPORATION (JP) 2010-03-04 WO disclosed
EP-0126231-B1 VINYLPHENYL BENZIMIDAZOLE DERIVATIVES, THEIR POLYMERS, THEIR PREPARATION AND USE Asahi Kasei Kogyo Kabushiki Kaisha (JP) 1989-12-20 EP disclosed
US-4533678-A BENZIMIDAZOLYLSTYRENE POLYMERS ASAHI KASEI KOGYO KABUSHIKI KAISHA (JP) 1985-08-06 US disclosed
EP-0126231-A2 Vinylphenyl benzimidazole derivatives, their polymers, their preparation and use Asahi Kasei Kogyo Kabushiki Kaisha (JP) 1984-11-28 EP disclosed