Known targets — ChEMBL curated mechanism
ADRA2AADRA2BADRA2CADRB2AGTR1AVPR1AAVPR1BAVPR2BDKRB2CALCRCHRNA3CHRNB4ESR1ESR2GHSRGNRHRGSC1HSPA8MALT1MC1RMC4RNOS1NOS2NOS3OPRK1OXTRRAMP1RAMP2RAMP3SCN5ASSTR1SSTR2SSTR3SSTR4SSTR5dacAdacBdacCfolPftsImrcAmrcBmrdArplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Acetic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 known ✓ | P03372 | 1/20 | 0.43 |
| ▸ | MAOA | P21397 | 2/20 | 0.43 |
| ▸ | MAOB | P27338 | 2/20 | 0.43 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.43 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.43 |
| ▸ | HMGB1 | P09429 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | GGT1 | P19440 | 1/20 | 0.43 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.43 |
| ▸ | BLM | P54132 | 1/20 | 0.43 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | ACSL1 | P33121 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL411459 | 0.97 | MAOA (0.46) | MAOAMAOBPTGS2KDM4EHSD17B10 | |
| Glycerin SCHEMBL8001701 | 0.91 | PTGS2 (0.36) | MAOAMAOBPTGS2KDM4EHSD17B10 | |
| Ether SCHEMBL1176750 | 0.90 | MAOA (0.39) | MAOAMAOBPTGS2KDM4EHSD17B10 | |
| SCHEMBL412590 | 0.86 | MAOA (0.43) | MAOAMAOBKDM4EHSD17B10ALDH1A1 | |
| SCHEMBL2715642 | 0.85 | MAOA (0.48) | MAOAMAOBKDM4EHSD17B10ALDH1A1 | |
| SCHEMBL28121382 | 0.85 | MAOA (0.42) | MAOAMAOBKDM4EHSD17B10ALDH1A1 | |
| Acetic Acid SCHEMBL1176753 | 0.84 | L3MBTL1 (0.43) | MAOAMAOBALDH1A1HPGDTDP1 | |
| SCHEMBL28671388 | 0.83 | MAOA (0.46) | MAOAMAOBKDM4EACSL1LMNA | |
| SCHEMBL7561920 | 0.82 | MAOA (0.42) | MAOAMAOBACSL1 | |
| SCHEMBL28207675 | 0.82 | MAOA (0.42) | MAOAMAOBKDM4EESR1ACSL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 852 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023123046-A1 | COMPOSITION FOR CARING FOR THE SKIN | L'OREAL (FR) | 2023-07-06 | — | — | WO | claimed |
| US-11426443-B2 | Compositions and methods for invasive and non-invasive procedural skincare | ALASTIN Skincare, Inc. (US) | 2022-08-30 | — | — | US | claimed |
| US-20210205405-A1 | COMPOSITIONS AND METHODS FOR INVASIVE AND NON-INVASIVE PROCEDURAL SKINCARE | ALASTIN Skincare, Inc. | 2021-07-08 | — | — | US | claimed |
| EP-3233044-B1 | ANHYDROUS COSMETIC COMPOSITION FOR TOPICAL APPLICATION IN INTIMATE AREAS | PROCTER & GAMBLE (US) | 2019-10-02 | — | — | EP | claimed |
| EP-2861206-B1 | COMPOSITION INCLUDING A PYRIDINE DICARBOXYLIC ACID ESTER AND A BINDING POLYMER, METHOD THEREFOR, AND USE THEREOF FOR TREATING HAIR | OREAL (FR) | 2019-06-12 | — | — | EP | claimed |
| CN-107854329-B | A kind of antibacterial moisturizing foam hand cleanser of easy wash type and preparation method thereof | 壹田（广州）生活健康用品有限公司 | 2019-02-01 | — | — | CN | claimed |
| EP-3386476-A1 | COMPOSITION COMPRISING A POLYMER CONTAINING A SULFONIC MONOMER AND A PYRIDINEDICARBOXYLIC ACID DERIVATIVE, AND COSMETIC TREATMENT METHOD | L'Oréal (FR) | 2018-10-17 | — | — | EP | claimed |
| CN-107854329-A | A kind of easily antibacterial moisturizing foam hand cleanser of wash type and preparation method thereof | 壹田（广州）生活健康用品有限公司 | 2018-03-30 | — | — | CN | claimed |
| CN-107822978-A | A kind of jelly film surface film containing growth factor and preparation method thereof | 广东科玮生物技术股份有限公司 | 2018-03-23 | — | — | CN | claimed |
| CN-107670027-A | Treat the composition and method of skin conditions | ZO皮肤健康公司 | 2018-02-09 | — | — | CN | claimed |
| US-6290987-B1 | ALKALI METAL ALKYL SULFATE, AT LEAST ONE MEMBRANE MIMETIC AMPHIPHILE, AND AT LEAST ONE PHOSPHOLIPID. | GENEREX PHARMACEUTICALS, INC. (CA) | 2001-09-18 | — | — | US | claimed |
| US-6271200-B1 | Proteinic drug delivery system using aerosolized membrane-mimetic amphiphiles | GENEREX PHARMACEUTICALS INC. (CA) | 2001-08-07 | — | — | US | claimed |
| EP-1115381-A1 | PROTEINIC DRUG DELIVERY SYSTEM USING MEMBRANE MIMETICS | Generex Pharmaceuticals Inc. (CA) | 2001-07-18 | — | — | EP | claimed |
| WO-2001017506-A1 | PROTEINIC DRUG DELIVERY SYSTEM USING MEMBRANE MIMETICS | GENEREX PHARMACEUTICALS INC. (CA) | 2001-03-15 | — | — | WO | claimed |
| US-6193997-B1 | HYALURONIC ACID AMPHIPHILE AND PHOSPHOLIPID; ADMINISTERING TO MOUTH AND NOSE MUCOUS MEMBRANES; LIPOSOME WITH MULTILAMELLAR VESICLES | GENEREX PHARMACEUTICALS INC. (CA) | 2001-02-27 | — | — | US | claimed |
| WO-2000037053-A1 | LARGE MOLECULE DRUG DELIVERY SYSTEM USING AEROSOLIZED MEMBRANE-MIMETIC AMPHIPHILES | GENEREX PHARMACEUTICALS INC. (CA) | 2000-06-29 | — | — | WO | claimed |
| WO-2000018371-A1 | PROTEINIC DRUG DELIVERY SYSTEM USING MEMBRANE MIMETICS | GENEREX PHARMACEUTICALS INC. (CA) | 2000-04-06 | — | — | WO | claimed |
| WO-1998026761-A9 | METHOD FOR TREATING HUMAN NAILS | — | 1998-10-29 | — | — | WO | claimed |
| WO-1998026761-A1 | METHOD FOR TREATING HUMAN NAILS | THE DIAL CORPORATION (US) | 1998-06-25 | — | — | WO | claimed |
| US-5635469-A | MANUAL LIQUID CLEANSER DISPENSER HAVING FOAM-PRODUCING NOZZLE; NON-AEROSOL | THE PROCTER & GAMBLE COMPANY (US) | 1997-06-03 | — | — | US | claimed |