SCHEMBL10607129

SCHEMBL10607129

CCOc1cc(N)ccc1NC(=O)c1ccc(N)cc1OCC

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 5/20 0.50
GAA P10253 5/20 0.50
TSHR P16473 2/20 0.50
MAPK1 P28482 2/20 0.50
HSD17B10 Q99714 2/20 0.50
KDM4E B2RXH2 2/20 0.50
LMNA P02545 1/20 0.50
HPGD P15428 1/20 0.50
ATM Q13315 1/20 0.50
NPSR1 Q6W5P4 1/20 0.50
KCNMA1 Q12791 2/20 0.48
MRGPRX1 Q96LB2 4/20 0.47
L3MBTL1 Q9Y468 2/20 0.47
MEN1 O00255 1/20 0.47
USP2 O75604 1/20 0.47
TP53 P04637 1/20 0.47
ALOX15 P16050 1/20 0.47
KMT2A Q03164 1/20 0.47
ALDH1A1 P00352 1/20 0.47
POLB P06746 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10604322 0.86 GAA (0.60) MAPTGAATSHRMAPK1KDM4E
SCHEMBL10607641 0.86 RAB9A (0.62) MAPTMAPK1HSD17B10KDM4ELMNA
SCHEMBL14440324 0.84 GAA (0.47) GAATSHRMRGPRX1MEN1KMT2A
SCHEMBL732657 0.84 KDM4E (0.49) MAPTGAATSHRHSD17B10KDM4E
SCHEMBL4521276 0.84 ALDH1A1 (0.56) MAPTGAAMAPK1HSD17B10KDM4E
SCHEMBL30847362 0.84 ALDH1A1 (0.56) MAPTGAAMAPK1HSD17B10KDM4E
SCHEMBL26557770 0.83 MAPT (0.62) MAPTGAAKDM4EL3MBTL1MEN1
SCHEMBL3850748 0.81 MAPT (0.63) MAPTGAAMAPK1KDM4EHPGD
SCHEMBL5991811 0.79 KMT2A (0.61) MAPTTSHRMAPK1LMNAHPGD
SCHEMBL2337419 0.79 TDP1 (0.62) MAPTGAATSHRHSD17B10KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4847353-A POLYAMIDEIMIDE COPOLYMERS NIPPON STEEL CHEMICAL CO., LTD. (JP) 1989-07-11 US disclosed