SCHEMBL10607641

SCHEMBL10607641

CCOc1cc(N)ccc1C(=O)Nc1ccc(N)cc1

nearest known ligand 0.62

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RAB9A P51151 6/20 0.62
NPC1 O15118 5/20 0.62
SMN1; SMN2 Q16637 4/20 0.62
TP53 P04637 3/20 0.62
MEN1 O00255 5/20 0.56
KMT2A Q03164 5/20 0.56
MAPT P10636 2/20 0.54
MAPK1 P28482 2/20 0.54
KLKB1 P03952 2/20 0.53
PLAU P00749 2/20 0.51
AHR P35869 1/20 0.51
F2 P00734 1/20 0.51
F10 P00742 1/20 0.51
PLAT P00750 1/20 0.51
TDP1 Q9NUW8 2/20 0.50
KCNK3 O14649 1/20 0.50
KCNK9 Q9NPC2 1/20 0.50
POLB P06746 1/20 0.50
APOBEC3A P31941 1/20 0.50
APOBEC3G Q9HC16 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10607129 0.86 MAPT (0.50) SMN1; SMN2TP53MEN1KMT2AMAPT
SCHEMBL10607122 0.85 RAB9A (0.61) RAB9ANPC1SMN1; SMN2TP53MEN1
SCHEMBL3850604 0.84 ALDH1A1 (0.61) RAB9ANPC1SMN1; SMN2MEN1KMT2A
SCHEMBL29530877 0.84 ALDH1A1 (0.61) RAB9ANPC1SMN1; SMN2MEN1KMT2A
SCHEMBL732657 0.84 KDM4E (0.49) RAB9ANPC1SMN1; SMN2TP53MAPT
SCHEMBL24074069 0.82 TSHR (0.61) RAB9ANPC1SMN1; SMN2TP53MAPT
SCHEMBL25383722 0.80 NPC1 (0.64) RAB9ANPC1SMN1; SMN2TP53MEN1
SCHEMBL17779250 0.80 NPC1 (0.67) RAB9ANPC1SMN1; SMN2TP53MEN1
SCHEMBL2337419 0.79 TDP1 (0.62) RAB9ANPC1SMN1; SMN2KMT2AMAPT
SCHEMBL578910 0.79 ALDH1A1 (0.67) RAB9ANPC1SMN1; SMN2MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4847353-A POLYAMIDEIMIDE COPOLYMERS NIPPON STEEL CHEMICAL CO., LTD. (JP) 1989-07-11 US disclosed