Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 5/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | ESR1 | P03372 | 1/20 | 0.53 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.53 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.53 |
| ▸ | HMGB1 | P09429 | 1/20 | 0.53 |
| ▸ | HPGD | P15428 | 1/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
| ▸ | GGT1 | P19440 | 1/20 | 0.53 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.53 |
| ▸ | BLM | P54132 | 1/20 | 0.53 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.53 |
| ▸ | TOP1 | P11387 | 2/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | ATM | Q13315 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31482993 | 1.00 | PTGS2 (0.53) | PTGS2KDM4EHSD17B10ALDH1A1ESR1 | |
| SCHEMBL6971901 | 0.84 | KDM4E (0.48) | KDM4EHSD17B10ALDH1A1HPGDPTGS1 | |
| SCHEMBL693858 | 0.83 | ACHE (0.56) | PTGS2KDM4EHSD17B10ALDH1A1ESR1 | |
| SCHEMBL8886874 | 0.82 | HSD17B10 (0.66) | PTGS2KDM4EHSD17B10ALDH1A1ESR1 | |
| SCHEMBL10499249 | 0.82 | PTGS2 (0.52) | PTGS2KDM4EHSD17B10ALDH1A1ESR1 | |
| SCHEMBL338196 | 0.80 | PTGS2 (0.68) | PTGS2KDM4EHSD17B10ALDH1A1ESR1 | |
| SCHEMBL29432883 | 0.80 | PTGS2 (0.68) | PTGS2KDM4EHSD17B10ALDH1A1ESR1 | |
| SCHEMBL24260340 | 0.79 | TOP1 (0.50) | PTGS2KDM4EHSD17B10ALDH1A1ESR1 | |
| SCHEMBL361663 | 0.79 | MAPT (0.59) | PTGS2KDM4EHSD17B10ALDH1A1ESR1 | |
| SCHEMBL24260332 | 0.79 | HSD17B10 (0.46) | KDM4EHSD17B10ALDH1A1ESR1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4238571-A1 | APPLICATION OF THYMIDINE DERIVATIVE IN PREPARATION OF DRUGS | OnQuality Pharmaceuticals China Ltd. (CN) | 2023-09-06 | — | — | EP | disclosed |
| EP-0183207-B1 | POROUS GLASS FIBERS WITH IMMOBILIZED BIOCHEMICALLY ACTIVE MATERIAL | PPG INDUSTRIES, INC. (US) | 1989-09-20 | — | — | EP | disclosed |
| US-4748121-A | Porous glass fibers with immobilized biochemically active material | PPG INDUSTRIES, INC. (US) | 1988-05-31 | — | — | US | disclosed |
| EP-0183207-A1 | Porous glass fibers with immobilized biochemically active material | PPG INDUSTRIES, INC. (US) | 1986-06-04 | — | — | EP | disclosed |