Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | MTNR1A | P48039 | 3/20 | 0.45 |
| ▸ | MTNR1B | P49286 | 3/20 | 0.45 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.45 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.43 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.42 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.42 |
| ▸ | PPARG | P37231 | 1/20 | 0.42 |
| ▸ | PPARA | Q07869 | 1/20 | 0.42 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.42 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7521457 | 0.83 | MTNR1A (0.44) | L3MBTL1MTNR1AMTNR1BEPHX2GRM2 | |
| SCHEMBL11619991 | 0.83 | AOC3 (0.45) | L3MBTL1MTNR1AMTNR1BEPHX2AOC3 | |
| SCHEMBL11616745 | 0.81 | AOC3 (0.59) | L3MBTL1MTNR1AMTNR1BAOC3ALOX5 | |
| SCHEMBL10608578 | 0.81 | MMP13 (0.47) | GRM2 | |
| SCHEMBL10607023 | 0.80 | L3MBTL1 (0.55) | L3MBTL1MTNR1AMTNR1BAOC3 | |
| SCHEMBL29195967 | 0.80 | SLC2A1 (0.50) | L3MBTL1MTNR1AMTNR1BAOC3 | |
| SCHEMBL11619897 | 0.80 | AOC3 (0.43) | L3MBTL1MTNR1AMTNR1BAOC3 | |
| SCHEMBL10610045 | 0.79 | MMP13 (0.45) | TAS1R3TAS1R1 | |
| SCHEMBL7311626 | 0.78 | KMT2A (0.43) | L3MBTL1MTNR1AMTNR1BEPHX2GRM2 | |
| SCHEMBL30167310 | 0.78 | KMT2A (0.43) | L3MBTL1MTNR1AMTNR1BEPHX2GRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0162208-B1 | NOVEL N-SUBSTITUTED 3,4-DIHYDROPYRIMIDINE DERIVATIVES, PROCESSES FOR PREPARING THEM AND PHARMACEUTICAL COMPOSITIONS | SUNTORY KABUSHIKI KAISHA, also known as SUNTORY LTD. (JP) | 1989-11-23 | — | — | EP | disclosed |
| US-4683234-A | HYPOTENSIVE AGENTS, ANTI-ANGINA | SUNTORY LIMITED (JP) | 1987-07-28 | — | — | US | disclosed |
| EP-0162208-A2 | Novel N-substituted 3,4-dihydropyrimidine derivatives, processes for preparing them and pharmaceutical compositions | SUNTORY KABUSHIKI KAISHA, also known as SUNTORY LTD. (JP) | 1985-11-27 | — | — | EP | disclosed |