Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.49 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 4/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 3/20 | 0.46 |
| ▸ | LMNA | P02545 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | ESR1 | P03372 | 1/20 | 0.43 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.43 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.43 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.43 |
| ▸ | FLT1 | P17948 | 1/20 | 0.43 |
| ▸ | FGFR3 | P22607 | 1/20 | 0.43 |
| ▸ | KDR | P35968 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10877944 | 0.90 | KMT2A (0.46) | KMT2AMEN1RXFP1VCAM1MAPT | |
| SCHEMBL22121312 | 0.89 | KMT2A (0.47) | KMT2AMEN1RXFP1VCAM1MAPT | |
| SCHEMBL645817 | 0.88 | VCAM1 (0.55) | KMT2AMEN1RXFP1VCAM1MAPT | |
| SCHEMBL10607220 | 0.87 | KMT2A (0.54) | KMT2AMEN1MAPTKDM4EPOLB | |
| SCHEMBL10609112 | 0.85 | ESR1 (0.55) | KMT2AMEN1MAPTKDM4EPOLB | |
| SCHEMBL8220838 | 0.84 | KMT2A (0.66) | KMT2AMEN1RXFP1VCAM1MAPT | |
| SCHEMBL10606746 | 0.83 | GAA (0.51) | KMT2AMEN1MAPTKDM4EPOLB | |
| SCHEMBL22081923 | 0.83 | MAPT (0.52) | KMT2AMEN1RXFP1VCAM1MAPT | |
| SCHEMBL30159180 | 0.83 | MAPT (0.52) | KMT2AMEN1RXFP1VCAM1MAPT | |
| SCHEMBL10487697 | 0.82 | KMT2A (0.49) | KMT2AMEN1RXFP1VCAM1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0206635-B1 | PREPARATION OF 3-AMINO-4-HYDROXYBENZOIC ACIDS | THE DOW CHEMICAL COMPANY (US) | 1989-11-15 | — | — | EP | disclosed |
| EP-0206635-A1 | Preparation of 3-amino-4-hydroxybenzoic acids | THE DOW CHEMICAL COMPANY (US) | 1986-12-30 | — | — | EP | disclosed |