Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 3/20 | 0.55 |
| ▸ | COMT | P21964 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.46 |
| ▸ | LMNA | P02545 | 4/20 | 0.46 |
| ▸ | RAB9A | P51151 | 3/20 | 0.46 |
| ▸ | GLA | P06280 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | CRHBP | P24387 | 1/20 | 0.43 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.43 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.43 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.41 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10607192 | 0.92 | ESR1 (0.53) | ESR1COMTALDH1A1LMNARAB9A | |
| SCHEMBL10607220 | 0.89 | KMT2A (0.54) | ESR1ALDH1A1LMNARAB9ANPSR1 | |
| SCHEMBL10609057 | 0.86 | ESR1 (0.55) | ESR1COMTALDH1A1LMNARAB9A | |
| SCHEMBL10609093 | 0.85 | KMT2A (0.49) | ESR1ALDH1A1LMNAKMT2AMEN1 | |
| SCHEMBL22121367 | 0.84 | ESR1 (0.53) | ESR1COMTALDH1A1LMNARAB9A | |
| SCHEMBL10487693 | 0.84 | ESR1 (0.55) | ESR1COMTALDH1A1LMNARAB9A | |
| SCHEMBL10610684 | 0.83 | ALDH1A1 (0.51) | ESR1ALDH1A1LMNARAB9ANPSR1 | |
| SCHEMBL11341084 | 0.81 | ESR1 (0.78) | ESR1COMTALDH1A1RAB9AMAPT | |
| SCHEMBL2655338 | 0.80 | KMT2A (0.57) | ESR1ALDH1A1LMNARAB9ANPSR1 | |
| SCHEMBL10606746 | 0.80 | GAA (0.51) | ALDH1A1LMNAKMT2AMEN1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0206635-B1 | PREPARATION OF 3-AMINO-4-HYDROXYBENZOIC ACIDS | THE DOW CHEMICAL COMPANY (US) | 1989-11-15 | — | — | EP | disclosed |
| EP-0206635-A1 | Preparation of 3-amino-4-hydroxybenzoic acids | THE DOW CHEMICAL COMPANY (US) | 1986-12-30 | — | — | EP | disclosed |