SCHEMBL10609096

SCHEMBL10609096

C1=Cc2nc1c(-c1cccc3cc4ccccc4cc13)c1ccc([nH]1)c(-c1cccc3cc4ccccc4cc13)c1nc(c(-c3cccc4cc5ccccc5cc34)c3ccc([nH]3)c2-c2cccc3cc4ccccc4cc23)C=C1

nearest known ligand 0.55

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
▸ TERT O14746 2/20 0.39
▸ STAT3 P40763 1/20 0.38
▸ STAT1 P42224 1/20 0.38
▸ TOP1 P11387 2/20 0.38
▸ CYCS P99999 3/20 0.37
▸ ENPP2 Q13822 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31055465 0.85 GSK3B (0.46) TERTTOP1CYCS
SCHEMBL31055464 0.85 GSK3B (0.46) TERTTOP1CYCS
SCHEMBL31055466 0.85 GSK3B (0.46) TERTTOP1CYCS
SCHEMBL4320743 0.85 GSK3B (0.46) TERTTOP1CYCS
SCHEMBL30679531 0.80 CES1 (0.38) TERTSTAT3STAT1TOP1CYCS
SCHEMBL9681352 0.80 TERT (0.42) TERTSTAT3STAT1TOP1CYCS
SCHEMBL18091353 0.79 TERT (0.41) TERTSTAT3STAT1TOP1CYCS
SCHEMBL27894995 0.76 CDK4 (0.44) TERTSTAT3STAT1TOP1CYCS
SCHEMBL224502 0.75 TERT (0.39) TERTTOP1CYCSENPP2
SCHEMBL17232299 0.75 GSK3B (0.40) TERT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4746735-A NITRATING AGENT, SOLVENT, SMALL AMOUNT OF SULFURIC ACID CATALYST THE DOW CHEMICAL COMPANY (US) 1988-05-24 — — US claimed
EP-3049502-B1 LONG-TERM STABLE PHOTOACTIVE COMPOSITION, SUCH AS PHOSPHORESCENT COMPOSITION OR TTA-PHOTON UPCONVERSION COMPOSITION MAX PLANCK GESELLSCHAFT (DE) 2020-04-01 — — EP disclosed
US-10400164-B2 Long-term stable photoactive composition, such as phosphorescent composition or TTA-photon upconversion composition MAX-PLANCK-Gesellschaft zur Förderung der Wissenschaften e.V. (DE) 2019-09-03 — — US disclosed
US-20160222286-A1 LONG-TERM STABLE PHOTOACTIVE COMPOSITION, SUCH AS PHOSPHORESCENT COMPOSITION OR TTA-PHOTON UPCONVERSION COMPOSITION MAX-PLANCK-Gesellschaft zur Förderung der Wissenschaften e.V. (DE) 2016-08-04 — — US disclosed
EP-3049502-A1 LONG-TERM STABLE PHOTOACTIVE COMPOSITION, SUCH AS PHOSPHORESCENT COMPOSITION OR TTA-PHOTON UPCONVERSION COMPOSITION Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. (DE) 2016-08-03 — — EP disclosed
WO-2015044129-A1 LONG-TERM STABLE PHOTOACTIVE COMPOSITION, SUCH AS PHOSPHORESCENT COMPOSITION OR TTA-PHOTON UPCONVERSION COMPOSITION MAX-PLANCK-Gesellschaft zur Förderung der Wissenschaften e.V. (DE) 2015-04-02 — — WO disclosed
EP-2851407-A1 Long-term stable photoactive composition, such as phosphorescent composition or TTA-photon upconversion composition Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. (DE) 2015-03-25 — — EP disclosed
US-4746735-A NITRATING AGENT, SOLVENT, SMALL AMOUNT OF SULFURIC ACID CATALYST THE DOW CHEMICAL COMPANY (US) 1988-05-24 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10400164-B2 Long-term stable photoactive composition, such as phosphorescent composition or TTA-photon upconversion composition TTPA, TCP1, TERB1 TERT 21/4885STAT3 2626/4885STAT1 2758/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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