SCHEMBL18091353

SCHEMBL18091353

C1=Cc2nc1c(-c1c3ccccc3cc3ccccc13)c1ccc([nH]1)c(-c1c3ccccc3cc3ccccc13)c1nc(c(-c3c4ccccc4cc4ccccc34)c3ccc([nH]3)c2-c2c3ccccc3cc3ccccc23)C=C1.[Pt]

nearest known ligand 0.50

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
▸ TERT O14746 2/20 0.41
▸ STAT3 P40763 1/20 0.41
▸ STAT1 P42224 1/20 0.41
▸ TOP1 P11387 2/20 0.41
▸ NISCH Q9Y2I1 1/20 0.40
▸ CYCS P99999 3/20 0.40
▸ ENPP2 Q13822 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9681352 0.98 TERT (0.42) TERTSTAT3STAT1TOP1NISCH
SCHEMBL18091350 0.81 STAT3 (0.54) TERTSTAT3STAT1TOP1NISCH
SCHEMBL30530582 0.79 TERT (0.41) TERTSTAT3STAT1TOP1CYCS
SCHEMBL10609096 0.79 TERT (0.39) TERTSTAT3STAT1TOP1CYCS
SCHEMBL8021991 0.79 PTPN22 (0.42) TERTTOP1CYCSENPP2
SCHEMBL31055464 0.76 GSK3B (0.46) TERTTOP1NISCHCYCS
SCHEMBL31055466 0.76 GSK3B (0.46) TERTTOP1NISCHCYCS
SCHEMBL4320743 0.76 GSK3B (0.46) TERTTOP1NISCHCYCS
SCHEMBL31055465 0.76 GSK3B (0.46) TERTTOP1NISCHCYCS
SCHEMBL1314979 0.74 TOP1 (0.62) TERTSTAT3STAT1TOP1CYCS

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10739334-B2 Capsule suitable for non-invasive simultaneous oxygen content and temperature sensing in a living object MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN E.V. (DE) 2020-08-11 — — US disclosed
EP-3274420-B1 CAPSULE SUITABLE FOR NON-INVASIVE SIMULTANEOUS OXYGEN CONTENT AND TEMPERATURE SENSING IN A LIVING OBJECT MAX PLANCK GESELLSCHAFT (DE) 2019-01-30 — — EP disclosed
US-20180106785-A1 CAPSULE SUITABLE FOR NON-INVASIVE SIMULTANEOUS OXYGEN CONTENT AND TEMPERATURE SENSING IN A LIVING OBJECT MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN E.V. (DE) 2018-04-19 — — US disclosed
EP-3072942-A1 CAPSULE SUITABLE FOR NON-INVASIVE SIMULTANEOUS OXYGEN CONTENT AND TEMPERATURE SENSING IN A LIVING OBJECT Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. (DE) 2016-09-28 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10739334-B2 Capsule suitable for non-invasive simultaneous oxygen content and temperature sensing in a living object SQOR, SIRT3, NQO1 TERT 846/4885STAT3 789/4885STAT1 1290/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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