Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 1/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.45 |
| ▸ | MEN1 | O00255 | 3/20 | 0.45 |
| ▸ | COMT | P21964 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 4/20 | 0.45 |
| ▸ | LMNA | P02545 | 3/20 | 0.45 |
| ▸ | GLA | P06280 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25255894 | 0.90 | KMT2A (0.50) | ESR1KDM4EPOLBMAPK1ALDH1A1 | |
| SCHEMBL10609057 | 0.84 | ESR1 (0.55) | ESR1KDM4EPOLBALDH1A1KMT2A | |
| SCHEMBL10609112 | 0.84 | ESR1 (0.55) | ESR1KDM4EPOLBMAPK1ALDH1A1 | |
| SCHEMBL1458078 | 0.84 | VCAM1 (0.49) | KDM4EPOLBMAPK1ALDH1A1KMT2A | |
| SCHEMBL10607192 | 0.82 | ESR1 (0.53) | ESR1KDM4EPOLBALDH1A1KMT2A | |
| SCHEMBL16841186 | 0.79 | LMNA (0.50) | MAPK1ALDH1A1KMT2AMEN1LMNA | |
| SCHEMBL4248118 | 0.79 | TPMT (0.57) | MAPK1ALDH1A1KMT2ASMN1; SMN2MEN1 | |
| SCHEMBL19436450 | 0.79 | MAPT (0.50) | KDM4EPOLBMAPK1ALDH1A1KMT2A | |
| SCHEMBL11341084 | 0.79 | ESR1 (0.78) | ESR1ALDH1A1COMTRAB9AMAPT | |
| SCHEMBL2655338 | 0.78 | KMT2A (0.57) | ESR1KDM4EPOLBMAPK1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020132582-A1 | STING AGONISTS AND USES THEREOF | NIMBUS TITAN, INC. (US) | 2020-06-25 | — | — | WO | disclosed |