Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRA | P10827 | 2/20 | 0.39 |
| ▸ | THRB | P10828 | 2/20 | 0.39 |
| ▸ | PDK2 | Q15119 | 2/20 | 0.37 |
| ▸ | PTPN11 | Q06124 | 4/20 | 0.37 |
| ▸ | NR5A1 | Q13285 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10608551 | 1.00 | THRA (0.39) | THRATHRBPDK2PTPN11NR5A1 | |
| SCHEMBL10612509 | 1.00 | THRA (0.39) | THRATHRBPDK2PTPN11NR5A1 | |
| SCHEMBL10612462 | 0.97 | ALDH1A1 (0.34) | THRATHRBPDK2PTPN11TSHR | |
| SCHEMBL10609372 | 0.88 | LMNA (0.39) | PDK2 | |
| SCHEMBL10610852 | 0.84 | PDK2 (0.37) | PDK2 | |
| SCHEMBL10610433 | 0.82 | AAK1 (0.41) | PDK2TSHR | |
| SCHEMBL10613200 | 0.81 | ALDH1A1 (0.38) | — | |
| SCHEMBL10608707 | 0.81 | CNR2 (0.37) | — | |
| SCHEMBL10611884 | 0.81 | CNR2 (0.37) | — | |
| SCHEMBL10612314 | 0.79 | NPC1 (0.45) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0271550-A1 | BENZOPYRAN AND BENZOTHIOPYRAN DERIVATIVES AND COMPOSITIONS CONTAINING THEM | ALKALOIDA VEGYéSZETI GYáR (HU) | 1988-06-22 | — | — | EP | disclosed |
| WO-1988000197-A1 | BENZOPYRAN AND BENZOTHIOPYRAN DERIVATIVES AND COMPOSITIONS CONTAINING THEM | ALKALOIDA VEGYE^´SZETI GYA^´R (HU) | 1988-01-14 | — | — | WO | disclosed |