Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | PIK3CD | O00329 | 2/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Tetrahydrofuran SCHEMBL28738577 | 0.97 | TSHR (0.50) | TSHRALDH1A1TDP1PIK3CDPKM | |
| Dioxane SCHEMBL28235404 | 0.88 | TSHR (0.60) | TSHRALDH1A1TDP1PIK3CDPKM | |
| Tetrahydrofuran SCHEMBL4133541 | 0.86 | TDP1 (0.56) | TSHRALDH1A1TDP1PKMSMN1; SMN2 | |
| Isobutanol SCHEMBL8679927 | 0.84 | — | — | |
| Tetrahydrofuran SCHEMBL10660627 | 0.83 | TDP1 (0.53) | TSHRALDH1A1TDP1PKMSMN1; SMN2 | |
| Isobutanol SCHEMBL28235407 | 0.82 | TSHR (0.53) | TSHRTDP1 | |
| 3-Methylbutanol SCHEMBL11793232 | 0.81 | ALDH1A1 (0.40) | TSHRALDH1A1PIK3CD | |
| Tetrahydrofuran SCHEMBL10386650 | 0.80 | ALDH1A1 (0.44) | TSHRALDH1A1TDP1PKMSMN1; SMN2 | |
| Tetrahydrofuran SCHEMBL28856284 | 0.79 | TSHR (0.39) | TSHRALDH1A1 | |
| Tetrahydrofuran SCHEMBL28255861 | 0.79 | ALDH1A1 (0.50) | TSHRALDH1A1PIK3CD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103848845-B | Prasugrel times semihydrate and preparation method thereof | Tianjin Hankang Pharmaceutical Biotechnology Co., Ltd. (CN) | 2015-12-23 | — | — | CN | claimed |
| CN-104650034-A | Stable axitinib compound | TIANJIN HANKANG PHARMACEUTICAL BIOTECHNOLOGY CO LTD | 2015-05-27 | — | — | CN | claimed |
| CN-104650086-A | Ponatinib hydrochloride compound | TIANJIN HANKANG PHARMACEUTICAL BIOTECHNOLOGY CO LTD | 2015-05-27 | — | — | CN | claimed |
| CN-103848845-A | Prasugrel sesquihydrate and preparation method thereof | TIANJIN HANKANG PHARMACEUTICAL BIOTECHNOLOGY CO LTD | 2014-06-11 | — | — | CN | claimed |
| EP-2627684-A1 | PROCESS FOR PREPARING A (METH)ACRYLATE COPOLYMER CONTAINING QUATERNARY AMMONIUM GROUPS BY FREE-RADICAL POLYMERIZATION IN SOLUTION | Evonik Röhm GmbH (DE) | 2013-08-21 | — | — | EP | claimed |
| US-20130096272-A1 | PROCESS FOR PREPARING A (METH)ACRYLATE COPOLYMER CONTAINING TERTIARY AMINO GROUPS BY FREE-RADICAL POLYMERIZATION IN SOLUTION | EVONIK ROEHM GMBH (DE) | 2013-04-18 | — | — | US | claimed |
| WO-2012048742-A1 | PROCESS FOR PREPARING A (METH)ACRYLATE COPOLYMER CONTAINING QUATERNARY AMMONIUM GROUPS BY FREE-RADICAL POLYMERIZATION IN SOLUTION | EVONIK RÖHM GMBH (DE) | 2012-04-19 | — | — | WO | claimed |
| EP-0296225-A1 | CARBAMOYLOXYLABDANES | HOECHST-ROUSSEL PHARMACEUTICALS INCORPORATED (US) | 1988-12-28 | — | — | EP | claimed |
| WO-1988005047-A1 | CARBAMOYLOXYLABDANES | HOECHST-ROUSSEL PHARMACEUTICALS INC. (US) | 1988-07-14 | — | — | WO | claimed |
| US-20200163328-A1 | DISPERSION FOR AN AQUEOUS SPRAY FORMULATION WITH CONTROLLED MECHANICAL DEGRADATION | GREENA B.V. (NL) | 2020-05-28 | — | — | US | disclosed |
| CN-103848845-B | Prasugrel times semihydrate and preparation method thereof | Tianjin Hankang Pharmaceutical Biotechnology Co., Ltd. (CN) | 2015-12-23 | — | — | CN | disclosed |
| CN-104650086-A | Ponatinib hydrochloride compound | TIANJIN HANKANG PHARMACEUTICAL BIOTECHNOLOGY CO LTD | 2015-05-27 | — | — | CN | disclosed |
| CN-104650034-A | Stable axitinib compound | TIANJIN HANKANG PHARMACEUTICAL BIOTECHNOLOGY CO LTD | 2015-05-27 | — | — | CN | disclosed |
| CN-103848845-A | Prasugrel sesquihydrate and preparation method thereof | TIANJIN HANKANG PHARMACEUTICAL BIOTECHNOLOGY CO LTD | 2014-06-11 | — | — | CN | disclosed |